Parameter value estimates
| Variable | Point estimate (%) | Range estimate (%) | Data source |
|---|---|---|---|
| POC vaginal | Primary data* | ||
| Sensitivity | 92.9 | 66.1–99.8 | |
| Specificity | 98.5 | 94.6–99.8 | |
| NAAT vaginal | 9 11 12 | ||
| Sensitivity | 98.0 | 96.9–100 | |
| Specificity | 97.8 | 96.5–100 | |
| Chlamydia prevalence | 9.4 | – | Primary data* |
| Patients willing to wait for POC test result | Primary data* | ||
| 40 min waiting | 47.5 | 38.8–56.5 | |
| 60 min waiting | 28.0 | 19.9–36.1 | |
| 90 min waiting | 15.3 | 8.8–21.7 | |
| Ct treatment received in POC strategy | Primary data* | ||
| Among women who wait for result | 100 | – | |
| Among women who do not wait for result | 93.7 | 80–100 | |
| Ct treatment received in NAAT strategy | 93.7 | 80–100 | Primary data* |
| Infected women requiring DIS effort in NAAT strategy | Primary data* | ||
| Received treatment | 59.2 | – | |
| Did not receive treatment | 100 | – | |
| Infected women requiring DIS effort in POC strategy | Primary data* | ||
| Received treatment at index visit | 0 | – | |
| Did not receive treatment at index visit | 100 | – | |
| Azithromycin treatment success rate | 97 | – | 4 |
| PID among chlamydia-infected women prior to testing | 3.6 | – | 13 14 |
| PID developing among chlamydia-infected women between testing and 2-week treatment visit | 2.2 | – | 15 |
| PID among women with untreated chlamydia | 30 | 23–41 | 16–19 |
| Silent PID among all PID | 60 | – | 8 |
| Inpatient treatment of PID | 11.8 | 9.0–14.5 | 20 21 |
| Chronic pelvic pain caused by PID | 22.9 | 16.7–29.0 | 22 23 |
| Ectopic pregnancy caused by PID | 4.2 | 0.6–9.1 | 22–26 |
| Infertility caused by PID | 9.7 | 8.0–11.4 | 24 26 |
| Infertile women seeking fertility services | 38.5 | 22.4–44.5 | 27 28 |
| POC test cost ($) | 33.48 | 20–50 | Estimated |
| NAAT test cost ($) | 33.48 | – | Medicaid reimbursement rate |
| Clinician cost for initial visit (20 min) ($) | 12.11 | – | 10 |
| Gloves ($) | 0.06 | – | 10 |
| Drape ($) | 0.30 | – | 10 |
| Cleaning room ($) | 1.01 | – | 10 |
| Vital signs ($) | 1.01 | – | 10 |
| Cost of medication (1 g azithromycin) ($) | 1.86 | – | 10 |
| Clinician cost for treating POC+onsite (10 min) ($) | 6.05 | – | 10 |
| Labour cost for women who needed DIS to assist with Ct treatment (1 h) ($) | 9.67 | – | 10 |
| Clinician cost for follow-up visit (20 min) ($) | 12.11 | – | 10 |
| Cost for PID inpatient treatment | 9 | ||
| In-hospital cost ($) | 10420 | 4968–15778 | |
| One 25 min outpatient follow-up visit ($) | 81.31 | – | |
| Cost for PID outpatient treatment | 9 | ||
| One 40 min initial visit ($) | 119.65 | – | |
| One 25-min follow-up visit ($) | 81.31 | – | |
| Ceftriaxone (250 mg) ($) | 23.23 | – | |
| Injection administration ($) | 5.81 | – | |
| Doxycycline (100 mg bid for 14 days) ($) | 3.48 | – | |
| Cost for infertility treatment ($)† ($) | 5957 | 4581–15676 | 9 |
| Cost for ectopic pregnancy treatment ($)‡ ($) | 7365 | 7365–9299 | 9 |
| Cost for chronic pelvic pain treatment ($)§ | 10527 | 766–19534 | 9 |
Costs are in US$ (in 2011).
*Results from our pilot study and/or survey results. The ranges for these values are the 95% CIs.
†Estimated delay of 10 years before cost realised.
‡Estimated delay of 5 years before cost realised.
§Estimated delay of 2 years before cost realised.
bid, twice daily; Ct, Chlamydia trachomatis; DIS, disease intervention specialist; NAAT, nucleic acid amplification test; PID, pelvic inflammatory disease; POC, point-of-care.