Table 1

Weighted seropositivities of human papillomavirus (HPV) vaccine types 6, 11, 16 and 18, of any HPV vaccine type, and of ≥3 HPV vaccine types among participants in the National Health and Nutrition Examination Surveys 2003–2006, by sex, age group and race/ethnicity

nSeropositivity by HPV type
HPV 6%(95% CI)HPV 11%(95% CI)HPV 16%(95% CI)HPV 18%(95% CI)Any HPV%(95% CI)≥3 HPV vaccine types %(95% CI)
Overall876712.3(11.2 to 13.6)4.7(3.9 to 5.5)10.2(9.5 to 10.9)3.7(3.1 to 4.3)22.5(21.1 to 23.9)1.7(1.4 to 2.1)
Female453117.5(15.6 to 19.6)6.8(5.8 to 8.1)15.1(13.8 to 16.4)5.9(4.9 to 7.0)31.8(29.6 to 34.2)2.8(2.2 to 3.4)
Age, years
 14–1914646.2(4.7 to 8.2)1.6(1.0 to 2.7)4.1(3.0 to 5.5)1.3(0.8 to 2.0)9.8(7.9 to 12.1)0.8(0.4 to 1.6)
 20–2450116.6(12.5 to 21.6)4.3(2.6 to 6.8)15.1(11.2 to 20.0)4.6(2.8 to 7.5)28.6(22.9 to 35.2)2.2(1.2 to 3.8)
 25–2946822.2(16.8 to 28.8)6.9(4.7 to 10.2)17.5(13.2 to 22.9)4.3(2.5 to 7.4)34.7(28.0 to 42.1)3.3(2.1 to 5.1)
 30–3977422.8(19.6 to 26.5)9.2(7.3 to 11.5)21.6(18.6 to 24.9)9.7(7.2 to 12.9)43.5(40.5 to 46.6)4.0(2.4 to 6.5)
 40–4974919.7(16.4 to 23.5)9.3(7.0 to 12.2)17.2(13.8 to 21.3)7.3(5.6 to 9.4)37.1(33.2 to 41.1)3.4(2.2 to 5.3)
 50–5957514.5(11.2 to 18.4)5.8(4.2 to 7.9)11.0(8.9 to 13.5)4.2(2.6 to 6.8)26.6(23.1 to 30.6)1.7*(1.0 to 3.4)
Race/ethnicity
 Non-Hispanic Caucasians185416.1(13.9 to 18.5)6.3(5.0 to 8.0)15.5(13.7 to 17.5)5.0(3.8 to 6.5)30.8(28.0 to 33.9)2.3(1.6 to 3.1)
 Non-Hispanic African-Americans118931.1(27.4 to 35.0)11.7(9.5 to 14.4)20.4(17.8 to 23.2)12.8(11.0 to 14.9)46.9(43.2 to 50.7)7.1(5.6 to 8.8)
 Mexican American148813.5(10.6 to 17.0)5.4(4.0 to 7.1)9.7(7.6 to 12.3)4.3(3.1 to 5.8)24.9(21.8 to 28.2)1.5(0.9 to 2.7)
Male42367.0(6.0 to 8.1)2.4(1.8 to 3.3)5.2(4.5 to 6.0)1.5(1.0 to 2.1)12.9(11.8 to 14.1)0.6*(0.3 to 1.2)
Age, years
 14–1915080.9*(0.4 to 2.0)0.1†(0.0 to 0.2)0.2†(0.1 to 0.4)<0.1†(0.00 to 0.2)1.2*(0.6 to 2.2)0
 20–243856.6(4.6 to 9.4)0.7†(0.2 to 1.8)1.0†(0.3 to 4.0)0.3†(0.1 to 1.2)8.3(5.8 to 11.6)0
 25–293673.7(2.1 to 6.4)2.3†(0.9 to 5.3)3.2(1.9 to 5.3)0.4†(0.1 to 1.5)7.9(5.2 to 11.9)0.3†(0.1 to 1.3)
 30–396919.0(6.9 to 11.7)3.0(1.8 to 4.8)6.6(5.0 to 8.5)1.8(1.2 to 2.8)15.7(13.1 to 18.8)0.9†(0.3 to 2.6)
 40–497228.9(6.8 to 11.5)3.2(1.9 to 5.4)9.3(6.9 to 12.4)2.4*(1.3 to 4.5)18.5(15.3 to 22.2)1.1†(0.4 to 3.1)
 50–595638.5(6.1 to 11.7)3.5(2.0 to 6.0)5.5(3.7 to 8.1)2.1*(1.0 to 4.1)16.0(12.3 to 20.6)0.6†(0.2 to 2.3)
Race/ethnicity
 Non-Hispanic Caucasians17026.3(5.0 to 7.8)2.3(1.5 to 3.5)5.7(4.7 to 6.9)1.2(0.7 to 2.1)12.4(10.7 to 14.4)0.6†(0.3 to 1.2)
 Non-Hispanic African-Americans11729.8(7.7 to 12.4)3.7(2.8 to 4.9)6.1(4.4 to 8.5)3.4(2.4 to 4.9)18.0(15.0 to 21.6)1.0*(0.5 to 2.4)
 Mexican American13627.9(6.1 to 10.2)2.2(1.3 to 3.7)2.9*(1.6 to 5.3)1.2*(0.5 to 2.6)11.7(9.3 to 14.6)0.4†(0.1 to 1.1)
  • *Relative standard error (RSE) 30–40%.

  • †RSE >40%.