Age-adjusted association between HPV status and cytological and histological abnormalities
| Cytology | Histology | ||||
| ASCUS (N=160), OR (95% CI) | LSIL (N=1478), OR (95% CI) | HSIL (N=724), OR (95% CI) | CIN1/NOS (N=360), OR (95% CI) | CIN2+ (N=697), OR (95% CI) | |
| HPV negative | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| LR-HPV only | 33.4 (17.7 to 63.3) | 4.2 (3.0 to 5.9) | 2.7 (1.1 to 6.8) | 7.1 (3.2 to 16.2) | 4.9 (1.5 to 16.6) |
| LR-HPV single | 36.6 (19.1 to 70.0) | 4.1 (2.9 to 5.9) | 2.5 (0.9 to 6.9) | 5.9 (2.3 to 15.2) | 3.8 (0.9 to 16.3) |
| LR-HPV multiple | 13.5 (1.8 to 101.5) | 4.8 (2.1 to 11.0) | 4.2 (0.6 to 30.2) | 14.9 (3.5 to 63.1) | 12.1 (1.6 to 91.0) |
| LR- + HR-HPV | 27.4 (15.5 to 48.5) | 12.2 (10.2 to 14.5) | 23.9 (17.2 to 33.3) | 29.8 (19.4 to 45.8) | 69.7 (43.0 to 113.1) |
Adjusted for age (linear).
LR, low-risk; HR, high-risk; NOS, not otherwise specified.