Factors* | Outcomes | Study sites | Overall test for interaction | |||
---|---|---|---|---|---|---|
Mudhol/Jamkhandi | Cotonou | Chennai | Kampala | |||
OR and 95% CI | OR and 95% CI | OR and 95% CI | OR and 95% CI | p Value | ||
Age <20 | IVF | – | – | – | 1.18 (0.43 to 2.92) | 0.05 |
BV | – | 3.71 (0.97 to 24.53) | – | 1.53 (0.79 to 3.03) | ||
HIV | IVF | 1.72 (0.16 to 18.48) | 3.38 (1.65 to 7.34) | 3.06 (1.38 to 6.79) | 1.28 (0.74 to 2.20) | 0.02 |
BV | 1.87 (0.52 to 7.34) | 3.07 (1.62 to 6.27) | 1.47 (0.73 to 3.03) | 1.25 (0.82 to 1.92) | ||
GC | IVF | – | 4.98 (1.26 to 33.3) | – | 0.88 (0.35 to 2.04) | 0.04 |
BV | – | 8.48 (2.47 to 53.54) | – | 1.21 (0.64 to 2.32) | ||
TV | IVF | – | – | 1.96 (0.46 to 7.76) | 3.14 (1.42 to 7.08) | 0.04 |
BV | – | – | 4.10 (1.56 to 12.85) | 1.76 (0.88 to 3.70) | ||
CV | IVF | – | 0.69 (0.29 to 1.62) | 0.66 (0.35 to 1.21) | 0.39 (0.23 to 0.66) | 0.03 |
BV | – | 0.45 (0.21 to 0.97) | 1.0 (0.62 to 1.62) | 0.43 (0.29 to 0.64) |
Results have been obtained from the final multivariate model which included in addition: Number of sexual acts/last 7 days ≥35, Current contraceptive method and Anal sex/past 30 days.
Blank cells correspond to invalid results due to cells with 0.
*Factors of which the product-term with the study sites had a significant association with vaginal flora abnormalities (p≤0.05).
BV, bacterial vaginosis (vs normal flora); CV, candidiasis; GC, gonorrhoea; IVF, intermediate vaginal flora (vs normal flora); OR, odds ratio (adjusted); TV, trichomoniasis.