HRs and 95% CIs for a diagnosis of cervical intraepithelial neoplasia grade 3 or worse (CIN3+) according to Chlamydia trachomatis (CT) status among 320 women with persistent human papillomavirus (HPV) infection at baseline
| n* | % CIN3+ | HR† | 95% CI | HR‡ | 95% CI | |
|---|---|---|---|---|---|---|
| CT DNA | ||||||
| Negative | 296 | 25.7 | 1 | 1 | – | |
| Positive | 23 | 13.0 | 0.51 | 0.16 to 1.63 | 0.53 | 0.17 to 1.70 |
| Self-reported CT infection | ||||||
| Never | 218 | 22.9 | 1 | 1 | – | |
| Ever | 102 | 29.4 | 1.39 | 0.88 to 2.18 | 1.38 | 0.87 to 2.18 |
| Self-reported number of CT infections | ||||||
| 0 | 218 | 22.9 | 1 | 1 | – | |
| 1 | 94 | 25.5 | 1.18 | 0.73 to 1.93 | 1.20 | 0.73 to 1.95 |
| ≥2 | 8 | 75.0 | 4.55 | 1.95 to 10.63 | 3.65 | 1.53 to 8.70 |
| trend | p=0.02 | p=0.02 | ||||
| Self-reported age at first CT infection (years) | ||||||
| Never | 218 | 22.9 | 1 | 1 | – | |
| ≥25 | 18 | 22.2 | 0.95 | 0.33 to 2.74 | 1.10 | 0.38 to 3.21 |
| 20–24 | 59 | 28.8 | 1.37 | 0.79 to 2.38 | 1.36 | 0.78 to 2.36 |
| ≤19 | 25 | 36.0 | 1.82 | 0.87 to 3.79 | 1.62 | 0.77 to 3.41 |
| Continuous (per year)§ | 0.89 | 0.79 to 1.00 | 0.91 | 0.81 to 1.03 | ||
*One woman had missing information on CT DNA status. No missing information concerning self-reported CT infection.
†Adjusted for age at baseline.
‡Adjusted for the baseline characteristics age, ever given birth, length of schooling and smoking status.
§Among women who reported CT infection.