Presenting symptoms and proctoscopic findings in rectal LGV cases and symptomatic controls
| Characteristic | Cases n (%) | Controls n (%) | OR (95% CI) | p Value |
|---|---|---|---|---|
| Total | 98 | 81 | ||
| Any rectal symptoms | 89 (91) | 81 (100) | n/a | |
| Duration: median days (IQR) | 13 (5–21) | 7 (3.5–14.5) | n/a | 0.146* |
| Anal discharge | 65 (66) | 36 (44) | 2.46 (1.34 to 4.51) | 0.004 |
| Rectal bleeding | 60 (61) | 41 (51) | 1.54 (0.85 to 2.79) | 0.155 |
| Anal pain | 55 (56) | 36 (44) | 1.60 (0.88 to 2.89) | 0.121 |
| Tenesmus | 32 (33) | 6 (7) | 6.06 (2.39 to 15.40) | <0.001 |
| Constipation | 29 (30) | 8 (10) | 3.84 (1.64 to 8.96) | 0.002 |
| Loose stools/diarrhoea | 28 (29) | 20 (25) | 1.22 (0.63 to 2.38) | 0.560 |
| Any constitutional symptoms | 33 (34) | 21 (26) | 1.45 (0.76 to 2.78) | 0.265 |
| Malaise | 19 (20) | 8 (10) | 2.19 (0.90 to 5.32) | 0.082 |
| Fever | 16 (16) | 8 (10) | 1.78 (0.72 to 4.40) | 0.213 |
| Weight loss | 11 (11) | 1 (1) | 10.10 (1.28 to 80.06) | 0.029 |
| Any genital or inguinal symptoms | 11 (11) | 12 (15) | 0.73 (0.30 to 1.75) | 0.476 |
| Proctoscopy findings† | 81 (91) | 73 (91) | ||
| Normal | 8 (10) | 16 (22) | 0.39 (0.16 to 0.97) | 0.044 |
| Proctitis | 52 (65) | 34 (47) | 2.08 (1.08 to 3.98) | 0.028 |
| Rectal bleeding | 31 (39) | 13 (18) | 2.87 (1.36 to 6.08) | 0.006 |
| Exudate | 47 (59) | 20 (28) | 3.70 (1.87 to 7.32) | <0.001 |
| Lesion or/ulcer | 13 (16) | 10 (14) | 1.22 (0.50 to 3.00) | 0.661 |
*Wilcoxon rank sum test for medians.
†Proctoscopy was not performed in 17 cases (9 asymptomatic, 1 unable to be performed because of pain, 2 had perianal lesions only, 1 declined, 4 reason not recorded) and 8 controls (2 because of pain, 3 perianal lesions, 1 abdominal cramps, 2 reason not recorded).
LGV, lymphogranuloma venereum.