Table 1

Mycoplasma genitalium and Chlamydia trachomatis* serum IgG antibodies in women and men of infertile couples and spontaneously pregnant women

Prevalence of antibodiesAssociation of antibodies with diagnoses
Cases
Pos. antibody/tested
Controls
Pos. antibody/tested
UnadjustedAdjusted†
n/NPer centn/NPer centOR95% CIOR†95% CI
Infertility, women‡
M. genitalium13/2395.44/2441.63.451.10 to 10.753.000.95 to 9.47
C. trachomatis*59/24424.238/24415.61.721.09 to 2.731.550.97 to 2.47
M. genitalium and C. trachomatis§9/1864.80/20202.141.92 to 2.39
TFI¶
M. genitalium4/449.19/1954.62.070.60 to 7.051.200.32 to 4.40
C. trachomatis*20/4643.539/19819.73.141.58 to 6.203.161.53 to 6.51
M. genitalium and C. trachomatis§4/2913.85/1573.24.861.22 to 19.36
Infertility, men
M. genitalium2/2430.8
C. trachomatis*49/24320.2
  • Serum was retrievable from 239 and 243 of the infertile women and men, respectively, and 244 of the control women, for M. genitalium IgG analysis.

  • Significant ORs highlighted in bold.

  • *C. trachomatis IgG antibodies are previously published5 and are included in the table for comparative reasons and the possibility to perform multivariate analysis.

  • †Variables included in the model were M. genitalium and C. trachomatis IgG serum antibodies. M. genitalium and C. trachomatis could not be included due to few/zero cases in some groups.

  • ‡Women from infertile couples compared with spontaneously pregnant women without infertility.

  • §Women positive to both M. genitalium and C. trachomatis IgG antibodies compared with women negative to both antibodies.

  • ¶Women with TFI diagnosed by laparoscopy and/or hysterosalpingosonography compared with all other women from infertile couples.

  • IgG, immunoglobulin G; TFI, tubal factor infertility.