Table 1

NG-MAST and MLST sequence types, and molecular antimicrobial resistance markers identified in gonococcal DNA extracted from clinical samples

SampleNG-MASTMLSTPolymorphism inPresence of
mtrR*†‡§penB*†penA genotype*†rpsJ§gyrA¶parC¶ponA*23S rRNA gene‡Penicillinase-encoding plasmid*TetM-encoding plasmid§
S199207363A39TA121GIIWTWTWTL421PWTNoNo
S287099363A39TWTIIV57MWTWTWTWTNoNo
S3211579Deletion of A**G120K A121GIX (D345a, A501V, P551L)V57MWTWTL421PC2611T (4)††NoNo
S4713811 430‡‡A39TWTIIWTWTWTWTWTNoNo
S512 424‡‡11 431‡‡A39TWTIIV57MS91F, D95AE91GWTWTYesNo
S6965411 428A39TWTIIV57MWTWTWTWTNoNo
S712 425‡‡8134A39TA121GIIV57MWTWTWTWTYesYes
S848221901Deletion of AG120K A121NXXXIV (Mosaic allele)V57MS91F, D95GS87RL421PC2611T (2)NoNo
S910 5589363A39TWTIIV57MWTWTWTWTNoNo
S1099097359A39TWTIIWTWTWTWTWTNoNo
S1141867359A39TWTIIWTWTWTWTWTNoNo
  • *Associated with decreased susceptibility/resistance to penicillin.

  • †Associated with decreased susceptibility to cephalosporins.

  • ‡Associated with decreased susceptibility to azithromycin.

  • §Associated with decreased susceptibility/resistance to tetracycline.

  • ¶Associated with decreased susceptibility to quinolones.

  • **Contains an A deletion in the 13 bp inverted repeat region of the mtrR promoter.

  • ††Parentheses indicate number of alleles with this mutation.

  • ‡‡STs not previously identified.

  • STs, sequence types; WT, wild type.