Table 1

Characteristics of patients with early syphilis according to their baseline HIV status.

n (%)Syphilis in HIV-positive
n=96 (47%)
Syphilis in HIV-negative
n=110 (53%)
p Value
Age, median years (IQR)37 (33–42)32 (28–40)0.0005
Syphilis stage0.57
 Primary (%)30 (31)34 (31)
 Secondary (%)18 (19)27 (25)
 Early latent (%)48 (50)49 (45)
Treatment with benzathine penicillin (%)86 (90)105 (95)0.11
Median number of sexual partners in last 3 month (IQR)4 (2–9)4 (2–7)0.91
Reported drug use (%)45 (47)42 (38)0.21
 Mephedrone (%)32 (33)33 (30)
 GHB/GBL (%)27 (28)24 (22)
 Crystal metamphetamine (%)28 (29)20 (18)
 Intravenous drug use (%)18 (19)17 (15)
Rectal chlamydia infection
(incidence/100 PYFU, CI)
50 (36–68)27 (19–36)0.004
Rectal gonorrhoea infection
(incidence/100 PYFU, CI)
66 (50–87)33 (25–44)0.004
Syphilis reinfection
(incidence/100 PYFU, CI)
26 (16–40)10 (5.7–17)0.004
HIV infection
(incidence/100 PYFU, CI)
n/a8.3 (4.2–14)
  • GHB/GBL, Gamma hydroxybutyrate/Gamma butyrolactone; PYFU, person-years of follow-up.