Performance of DPP Syphilis Screen & Confirm Assay (Chembio Diagnostics Systems)
| Study | Sample | Parameters % (95% CI) | DPP Treponemal line | DPP Non-treponemal line |
| Castro et al 20 | Banked serum samples | Sensitivity | 96.5 (NA) | 98.4 (NA) |
| Specificity | 95.5 (NA) | 98.6 (NA) | ||
| Yin et al 21 | Whole blood (n=1323) | Sensitivity | 96.7 (95.1–97.9) | 87.2 (84.0–89.9) |
| Specificity | 99.3 (98.3–99.7) | 94.4 (92.6–95.8) | ||
| Finger prick blood (n=488) | Sensitivity | 96.4 (93.5–98.0) | 85.5 (82.4–89.4) | |
| Specificity | 96.4 (93.5–98.0) | 96.1 (92.9–97.9) | ||
| Blood plasma (n=1323) | Sensitivity | 94.6 (92.5–96.1) | 88.4 (85.3–90.9) | |
| Specificity | 99.6 (98.7–99.9) | 95.0 (93.3–96.3) | ||
| Causer et al 22 | Serum (n=1005) | Sensitivity | 89.8% (87.3–91.9) | 94.2 (91.8–96.0) |
| Specificity | 99.3% (97.0–99.9) | 62.2 (57.5–66.6) |
NA, not applicable.