Table 4

TPP—combined TP and non-TP POCT for syphilis

Goal of testTo detect TP-specific antibodies and non-TP-specific antibodies
Intended use and target patient*Surveillance/case management: sexually active population, including key populations (eg, MSM, SW, STI clinic/service attendees)
Screening: pregnant women, key populations
Target use settingTo detect TP-specific antibodies and non-TP-specific antibodies
ResultsClear reactive, non-reactive or invalid result with minimal instructions for interpretation
EquipmentSingle-use diagnostic test preferred, reader optional (small, portable, tabletop or handheld, no electricity/power supply required)
Target use(s) TP component Non-TP component
Reference technologyTPPARPR