Multivariable linear regression predicting interleukin-10 (IL-10) and rapid plasma regain (RPR) at baseline visit* (prospective study)
| IL-10 | RPR | |||
| Coef. | p Value | Coef. | p Value | |
| Syphilis stage | ||||
| Primary | Ref | |||
| Secondary | −0.56 | 0.175 | 0.31 | 0.043 |
| Early latent | −1.67 | 0.001 | −0.03 | 0.866 |
| Late latent | −1.66 | 0.003 | 0.09 | 0.647 |
| Initial syphilis† | 1.29 | 0.001 | −0.44 | 0.001 |
| HIV‡ | 1.70 | 0.001 | −0.08 | 0.643 |
| HIV viral load§ | −0.03 | 0.603 | 0.03 | 0.174 |
| Coinfection¶ | 0.99 | 0.151 | 0.16 | 0.523 |
*Values of IL-10 have been log transformed and RPR square-root transformed.
†Comparison group is those with repeat syphilis at baseline visit.
‡HIV coded as 0=negative, 1=positive.
§HIV viral load in copies per millilitre. Continuous variable log transformed.
¶Presence of Neisseria gonorrhoeae or Chlamydia trachomatis at baseline visit. Coded 0=both absent, 1=either present.
IL, interleukin; RPR, rapid plasma reagin.