| Before or at time of starting PrEP |
Fourth-generation venous blood HIV test. Consider POCT and start PrEP same day if negative. HBV (Hepatitis B Virus) surface antigen (and start vaccination if immunity unknown; on-demand Truvada is not recommended in chronic hepatitis B infection, and if continuous PrEP is started, hepatology review is required before cessation). Hepatitis C serology. Serum creatinine and eGFR. Urinalysis. Baseline bone profile (alkaline phosphatase, calcium and phosphate) on bloods with history of osteoporosis risk factors.
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| While on PrEP |
3-monthly fourth-generation venous blood HIV test ± POCT (Point of Care test). 3-monthly STI screen for MSM, as per BASHH 2014 MSM guidance; STI screen as appropriate for heterosexuals. Urinalysis every visit (further investigation if protein 1+ or more). Annual creatinine/eGFR (more frequent if abnormal at baseline or proteinuria or >50, or on concomitant medications that are relevant to renal function).
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