Table 3

Univariable multinomial logistic analysis of latent class membership among CAP007 adolescent females with HIV-negative serostatus in 2011 (n=1049)

Risk variable	‘Low risk’ vs ‘no risk’ (Ref) (n=399)			‘High risk’ vs ‘no risk’ (Ref) (n=103)
Risk variable	β (SE)	P value	OR (95% CI)	β (SE)	P value	OR (95% CI)
HSV-2 status		<0.0001			<0.0001
Positive	0.70 (0.27)	0.0087	2.02 (1.20 to 3.42)	2.16 (0.30)	<0.0001	8.64 (4.79 to 15.59)
Negative	–	–	Ref	–	–	Ref
Contraception (past year)		<0.0001			<0.0001
Condom use	13.97 (19.62)	0.4764	1.17e+06 (2.34e−11 to 5.85e+22)	2.37 (0.27)	<0.0001	10.72 (6.33 to 18.18)
Other contraception	24.57 (39.25)	0.5314	4.67e+10 (1.82e−23 to 1.20e+44)	−4.93 (0.03)	<0.0001	0.01 (0.01 to 0.01)
None	–	–	Ref	–	–	Ref
HIV knowledge		0.4378			0.4378
Low	−0.24 (0.23)	0.291	0.79 (0.50 to 1.23)	0.18 (0.42)	0.6661	1.20 (0.52 to 2.74)
High	–	–	Ref	–	–	Ref
Prior HIV testing		0.7658			0.7658
Yes	0.00 (0.20)	0.9997	1.00 (0.67 to 1.49)	−0.49 (0.39)	0.2126	0.61 (0.29 to 1.32)
No	–	–	Ref	–	–	Ref
Financial dependence		0.5206			0.5206
Yes	0.06 (0.21)	0.7875	1.06 (0.70 to 1.59)	–0.38 (0.39)	0.3326	0.68 (0.32 to 1.48)
No	–	–	Ref	–	–	Ref
Drug use (past year)		<0.0001			<0.0001
At least once	7.12 (6.71)	0.2887	1231.57 (0.00 to 6.30e+08)	8.62 (6.71)	0.1987	5553.30 (0.01 to 2.85e+09)
Never	–	–	Ref	–	–	Ref
Alcohol use (past year)		<0.0001			<0.0001
At least once	1.09 (0.23)	<0.0001	2.98 (1.91 to 4.66)	3.33 (0.28)	<0.0001	27.83 (16.24 to 47.72)
Never	–	–	Ref	–	–	Ref
Pregnancy (past year)		<0.0001			<0.0001
Yes	1.86 (0.42)	0.0022	6.43 (2.80 to 14.77)	1.36 (0.60)	<0.0001	3.90 (1.21 to 12.53)
No	–	–	Ref	–	–	Ref
School absence (past year)		<0.0001			<0.0001
Illness	–0.04 (0.17)	0.7993	0.96 (0.69 to 1.33)	0.87 (0.33)	0.0079	2.40 (1.26 to 4.58)
Illness and other reason	0.35 (0.18)	0.0563	1.42 (0.99 to 2.03)	0.87 (0.37)	0.0188	2.39 (1.16 to 4.94)
Other reason	0.39 (0.20)	0.0556	1.48 (0.99 to 2.20)	1.96 (0.33)	<0.0001	7.10 (3.68 to 13.69)
None	–	–	Ref	–	–	Ref
Perceived HIV risk		<0.0001			<0.0001
High risk	–3.58 (434.29)	0.9934	0.03 (0.00 to Inf)	1.38 (0.27)	<0.0001	3.98 (2.37 to 6.70)
Low risk	24.73 (32.45)	0.4460	5.51e+10 (1.30e–17 to 2.32e+38)	–5.01 (738.00)	0.9946	0.01 (0.00 to Inf)
Not at risk	–	–	Ref	–	–	Ref
Age		<0.0001			<0.0001
≥18	1.13 (0.16)	<0.0001	3.09 (2.28 to 4.21)	2.01 (0.23)	<0.0001	7.49 (4.75 to 11.79)
<18	–	–	Ref	–	–	Ref

HSV-2, herpes simplex virus serotype-2; Ref, referent.