Table 1

Sensitivity and specificity of RPR, NT-MAA, TP-PA and EIA

Specimens	Non-treponemal tests						Treponemal tests
	NT-MAA			RPR			TP-PA			EIA
	Sensitivity
	n	%	95% CI	n	%	95% CI	n	%	95% CI	n	%	95% CI
Primary stage (n=13)	13	100	77.2 to 100	13	100	77.2 to 100	13	100	77.2 to 100	12	92.3	66.7 to 98.6
Secondary stage (n=43)	41	95.3	84.5 to 98.7	41	95.3	84.5 to 98.7	43	100	91.8 to 100	43	100	91.8 to 100
Early latent stage (n=28)	27	96.4	82.3 to 99.4	28	100	87.9 to 100	28	100	87.9 to 100	28	100	87.9 to 100
Late latent stage (n=43)	34	79.1	64.8 to 88.6	30	69.8	54.9 to 0.814	43	100	91.8 to 100	43	100	91.8 to 100
Overall sensitivity (N=127)	115	90.6	84.2 to 94.5	112	88.2	81.4 to 92.7	127	100	97.1 to 100	126	99.2	95.7 to 99.9
	Specificity
Non-reactive (n=244)	236	96.7	93.7–98.3	244	100	98.5–100	244	100	98.5–100	244	100	98.5–100

EIA=TrepSure Enzyme Immunoassay.NT-MAA, non-treponemal magnetic particle-based agglutination assay; RPR, rapid plasma reagin; TP-PA, Treponema pallidum particle agglutination assay.