Table 1

Characteristics of male blood donors with syphilis, July 2018 to June 2019 (n=46)

Donation month	Donor type	Age group	Ethnicity§	Possible source of infection and likely timing	Male partners	Syphilis status	Evidence of PrEP use
07/2018	Repeat	31–40	White British	Two new female partners	No	Past	No
07/2018	First-time	51–60	Asian	None identified	No	Past	No
08/2018	Repeat	61–70	White British	New sexual female partner; 2 months ago	No	Acute	No
09/2018	First-time	21–30	White British	None identified	No	Past	No
09/2018	First-time	41–50	White Other	None identified	No	Past	No
09/2018	First-time	41–50	White British	New sexual male partner; 3–6 months ago	Yes	Acute	No
10/2018	First-time	31–40	White British	Known past syphilis	No	Past	No
10/2018	First-time	61–70	White British	None identified	No	Past	No
11/2018	Repeat	61–70	White British	None identified	No	Past	No
11/2018	First-time	31–40	White British	Known past syphilis	No	Past	No
11/2018	Repeat	31–40	White British	Wife diagnosed with syphilis	No	Acute	No
11/2018	First-time	31–40	White British	Known past syphilis	No	Past	No
11/2018	First-time	51–60	Black African	Known past syphilis	No	Past	Yes*
12/2018	First-time	21–30	Black African	None identified	No	Past	No
12/2018	Repeat	21–30	White British	Male partners	Yes	Past	No
01/2019	Repeat	51–60	White British	New sexual female partner; few months ago	No	Acute	No
01/2019	Repeat	51–60	White British	New sexual female partner; few weeks ago	No	Acute	No
01/2019	Repeat	31–40	White British	New sexual female partner; 5 months ago	No	Acute	No
01/2019	Repeat	51–60	White British	None identified	Yes	Past	No
02/2019	First-time	21–30	White British	None identified	Yes	Acute	No
02/2019	Repeat	41–50	White British	None identified	No	Acute	No
02/2019	First-time	41–50	White Other	Known past syphilis	No	Past	No
02/2019	Repeat	51–60	Unknown	New sexual female partner; few months ago	No	Acute	No
02/2019	First-time	21–30	White British	No response	No	Past	No
03/2019	Repeat	41–50	White British	Known past syphilis (year ago)	Yes	Past	Yes†
03/2019	Repeat	41–50	White British	New sexual female partner; 1 month ago	No	Acute	No
03/2019	First-time	31–40	White British	Known past syphilis	Yes	Past	No
03/2019	First-time	31–40	Other	Known past syphilis	No	Past	No
03/2019	First-time	41–50	Asian	None identified	No	Past	No
04/2019	First-time	31–40	White Other	No response	Yes	Past	Yes‡
04/2019	First-time	31–40	White Other	Known past syphilis	Yes	Past	No
04/2019	Repeat	41–50	Asian	None identified	No	Past	No
04/2019	First-time	31–40	Asian	Known past syphilis	No	Past	No
04/2019	First-time	31–40	White British	Known past syphilis	Yes	Past	No
05/2019	First-time	31–40	White Other	None identified	No	Past	No
05/2019	First-time	51–60	Asian	None identified	No	Past	No
05/2019	First-time	31–40	White British	None identified	No	Past	No
05/2019	First-time	41–50	White Other	Known past syphilis	Yes	Past	No
05/2019	Repeat	21–30	White British	Male partner	Yes	Acute	No
05/2019	Repeat	31–40	White British	Male partners	Yes	Past	No
05/2019	First-time	61–70	White British	Female partners	No	Past	No
06/2019	First-time	31–40	White Other	Female partners	No	Acute	No
06/2019	First-time	31–40	Asian	None identified	No	Past	No
06/2019	First-time	21–30	White British	Male partner years ago, now female partners	Yes	Acute	No
06/2019	First-time	41–50	Black African	Known past syphilis	No	Past	No
06/2019	First-time	51–60	Asian	None identified	No	Past	No

Known past syphilis infection is marked in red; past syphilis is a contra-indication for blood donation.
*TFV 73.58 ng/mL, FTC 748.46 ng/mL.
†TFV 210.52 ng/mL, FTC 412.78 ng/mL.
‡TFV 39.96 ng/mL, FTC not detected.
§Asians included individuals born India (n=4), Pakistan (n=2) and Bangladesh (n=1); White Other included those born in Romania (n=4) and one born in Turkey, Luxembourg and Spain; Black Africans were from Ghana (n=1) and Uganda (n=1); an indivual classed as Other was born in Brazil.
FTC, emtricitabine; PrEP, pre-exposure prophylaxis; TFV, tenofovir.