Table 2

Associations between nadir, median and trajectory CD4 counts with anogenital ulcer disease (HAUD)

Model 1 (n=3947)OR (95% CI)P value
Nadir CD4 group (cells/µL)
<2001.2 (0.8 to 1.7)0.34
200–5001.0 (0.8 to 1.3)0.98
≥500Reference
Median CD4 group
<2002.1 (1.5 to 3.0)<0.0001
200–5001.3 (1.0 to 1.7)0.052
≥500Reference
CD4 trajectory group
Group 12.6 (1.5 to 4.4)0.0004
Group 21.3 (0.8 to 2.0)0.24
Group 31.4 (0.9 to 2.0)0.13
Group 42.5 (1.4 to 4.3)0.0012
Group 51.2 (0.9 to 1.6)0.27
Group 6Reference
Model 2 (n=3809)
Nadir CD4 group (cells/µL)
<2001.3 (0.9 to 1.9)0.16
200–5001.0 (0.8 to 1.4)0.74
≥500Reference
Median CD4 group
<2002.3 (1.6 to 3.2)<0.0001
200–5001.3 (1.0 to 1.7)0.041
≥500Reference
CD4 trajectory group
Group 12.9 (1.7 to 5.0)<0.0001
Group 21.4 (0.9 to 2.2)0.15
Group 31.5 (1.0 to 2.2)0.066
Group 42.5 (1.4 to 4.5)0.0018
Group 51.2 (0.9 to 1.6)0.27
Group 6Reference

  • Both models 1 and 2 were controlled for ages at baseline, HIV diagnosis, HAUD, median years of follow-up, gender and HIV risk factors.

  • HAUD, herpetic anogenital ulcer disease.