Table 1

Baseline characteristics

CharacteristicAll patients
(n=138)
Patients with HIV
(n=112)
Patients without HIV
(n=26)
Age (years)*43 (34–49)44 (36–50)34 (27–43)
Male sex126 (91.3%)112 (100%)14 (53.8%)
CD4 counts (/μL)*481 (351.3–575.3)
HIV-RNA <50 copies/mL90 (80.4%)
History of syphilis57 (41.3%)57 (50.1%)0 (0%)
Stage of syphilis
 111 (8.0%)6 (5.4%)5 (19.2%)
 269 (50.0%)59 (52.7%)10 (38.5%)
 Early latent35 (25.4%)32 (28.6%)3 (11.5%)
 Late latent8 (5.8%)4 (3.6%)4 (15.4%)
 Unknown duration15 (10.9%)11 (9.8%)4 (15.4%)
Baseline RPR titre (RU)*108.3 (58.3–218.9)129.8 (60.6–247.5)77.8 (53.6–113.1)
Baseline TPLA titre (TU)*6109 (2933–17 918)8234 (3325–23 571)3435 (640–5272)
Treatment duration (week)*4.5 (4–8)4 (4–8)6 (4–8)
Serological cure†131 (94.9%)105 (93.8%)26 (100%)
Switch to other regimens2 (1.4%)0 (0%)2 (7.7%)
  • *Median (IQR).

  • †Serological cure was defined as a ≥fourfold decrease in the RPR titre within 12 months in symptomatic early syphilis and 24 months in latent syphilis.

  • RPR, rapid plasma reagin; TPLA, Treponema pallidum latex-agglutination.