Sensitivity and specificity analyses of different sampling HPV tests, using PCR test as the reference (N=211)
| PCR test | Sensitivity, % (95% CI) | P value* | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) | |||
| Negative (%) | Positive (%) | Total (%) | ||||||
| Clinician-sampled test | ||||||||
| Negative | 108 (51.2) | 12 (5.7) | 120 (56.9) | 88.3 (80.2 to 93.6) | 0.1227 | 100.0 (95.7 to 100.0) | 100.0 (95.0 to 100.0) | 90.0 (82.8 to 94.5) |
| Positive | 0 (0.0) | 91 (43.1) | 91 (43.1) | |||||
| Total | 108 (51.2) | 103 (48.8) | 211 (100.0) | |||||
| Self-sampled test | ||||||||
| Negative | 108 (51.2) | 22 (10.4) | 130 (61.6) | 78.6 (69.2 to 85.9) | 100.0 (95.7 to 100.0) | 100.0 (94.4 to 100.0) | 83.1 (75.3 to 88.9) | |
| Positive | 0 (0.0) | 81 (38.4) | 81 (38.4) | |||||
| Total | 108 (51.2) | 103 (48.8) | 211 (100.0) | |||||
*McNemar’s χ2 test was done to compare sensitivity values between clinician-sampled and self-sampled tests.
HPV, human papillomavirus; NPV, negative predictive value; PPV, positive predictive value.