Performance of different sampling tests among study participants with different risks of HPV infections, using PCR test as the reference
| Self-sampled test | Clinician-sampled test | P value* | ||||
| High-risk HPV | Low-risk HPV | High-risk HPV | Low-risk HPV | High-risk HPV | Low-risk HPV | |
| Sensitivity, % (n/N) (95% CI) | 77.2 (61/79) (66.1 to 85.6) | 87.5 (35/40) (72.4 to 95.3) | 88.6 (70/79) (79.0 to 94.3) | 90.0 (36/40) (75.4 to 96.7) | 0.1237 | 1.0000 |
| Specificity, % (n/N) (95% CI) | 100.0 (108/108) (95.7 to 100.0) | 100.0 (108/108) (95.7 to 100.0) | 100.0 (108/108) (95.7 to 100.0) | 100.0 (108/108) (95.7 to 100.0) | ||
| PPV, % (n/N) (95% CI) | 100.0 (79/79) (92.6 to 100.0) | 100.0 (40/40) (87.7 to 100.0) | 100.0 (79/79) (93.5 to 100.0) | 100.0 (40/40) (88.0 to 100.0) | ||
| NPV, % (n/N) (95% CI) | 96.4 (108/112) (90.6 to 98.8) | 86.4 (108/125) (78.8 to 91.6) | 97.3 (108/111) (91.7 to 99.3) | 93.1 (108/116) (86.4 to 96.8) | ||
*McNemar’s χ2 test was done to compare sensitivity values between clinician-sampled and self-sampled tests.
HPV, human papillomavirus; NPV, negative predictive value; PPV, positive predictive value.