Sensitivity, specificity and DOR of Chlamydia trachomatis and Neisseria gonorrhoeae self-sampling-based tests with associated 95% CIs, I2 metric and p values
| Sensitivity (95% CIs) | P value | Specificity (95% CI) | P value | DOR (95% CI) | I2 | ||
| C. trachomatis | Overall | 88.2 (81.9–92.6) | Ref | 99.3 (98.9–99.5) | Ref | 1110 (472–2220) | 87.6 |
| Sampling site | Vaginal | 79.6 (62.1–90.3) | Ref | 99.0 (98.2–99.5) | Ref | 479 (124–1290) | 84.2 |
| Pharyngeal | 92.5 (86.5–95.9) | 0.20 | 99.7 (99.5–99.8) | 0.02 | 4550 (1710–9880) | 0.0 | |
| Rectal | 93.1 (87.8–96.2) | 0.01 | 99.4 (98.8–99.7) | 0.25 | 2490 (638–6770) | 79.0 | |
| Study population | Women | 85.0 (73.5–92.1) | 0.30 | 99.3 (98.7–99.6) | 0.74 | 895 (262–2260) | 87.1 |
| MSM | 91.6 (84.9–95.5) | Ref | 99.2 (98.8–99.4) | Ref | 1390 (551–2940) | 21.0 | |
| N. gonorrhoeae | Overall | 88.9 (84.2–92.3) | 0.79 | 99.1 (98.6–99.4) | 0.38 | 937 (459–1710) | 78.3 |
| Sampling site | Vaginal | 79.9 (68.6–87.9) | Ref | 99.1 (98.4–99.5) | Ref | 502 (182–1120) | 70.8 |
| Pharyngeal | 94.3 (89.6–96.9) | 0.003 | 99.3 (97.1–99.8) | 0.99 | 3370 (422–12 600) | 70.8 | |
| Rectal | 91.6 (86.0–95.1) | 0.01 | 99.2 (98.4–99.6) | 0.88 | 1620 (426–4340) | 63.8 | |
| Study population | Women | 83.5 (74.1–89.9) | 0.026 | 99.3 (98.8–99.6) | 0.033 | 838 (298–1890) | 73.6 |
| MSM | 92.9 (88.1–95.9) | Ref | 97.7 (96.9–98.3) | Ref | 573 (307–980) | 46.2 |
Significant values are bolded.
DOR, diagnostic OR; MSM, men who have sex with men.