No vaccination (n=7432) | HBV vaccination (n=3249) | Univariable OR (95% CI) | P value | Multivariable aOR (95% CI) | ||||
n (mean) | Col % (SD) | n (mean) | Col % (SD) | Row % | ||||
Age | 32.2 | 9.3 | 29.8 | 9 | – | 0.87 (0.85, 0.89) | <0.0001 | 0.87 (0.85, 0.89) |
Ethnicity | <0.0001 | |||||||
White | 5216 | 70 | 2312 | 71 | 31 | Ref | Ref | |
Mixed | 430 | 6 | 167 | 5 | 28 | 0.88 (0.73, 1.05) | 0.77 (0.63, 0.95) | |
Asian | 352 | 5 | 80 | 2 | 19 | 0.51 (0.40, 0.66) | 0.63 (0.45, 0.89) | |
Black | 329 | 4 | 124 | 4 | 27 | 0.85 (0.69, 1.05) | 0.83 (0.64, 1.06) | |
Other | 267 | 4 | 174 | 5 | 39 | 1.47 (1.21, 1.79) | 1.42 (1.14, 1.76) | |
Unknown | 838 | 11 | 392 | 12 | 32 | 1.06 (0.93, 1.20) | 1.04 (0.89, 1.22) | |
Region of birth | <0.0001 | |||||||
UK | 3236 | 44 | 1392 | 43 | 30 | Ref | Ref | |
Europe excluding UK | 1987 | 27 | 871 | 27 | 30 | 1.02 (0.92, 1.13) | 0.87 (0.77, 0.98) | |
Africa | 120 | 2 | 48 | 1 | 29 | 0.93 (0.66, 1.31) | 1.02 (0.69, 1.53) | |
Asia | 333 | 4 | 85 | 3 | 20 | 0.59 (0.46, 0.76) | 0.99 (0.71, 1.40) | |
Australasia | 63 | 1 | 16 | 0.5 | 20 | 0.59 (0.34, 1.03) | 0.53 (0.28, 0.97) | |
North America | 41 | 1 | 8 | 0.2 | 16 | 0.45 (0.21, 0.97) | 0.49 (0.22, 0.97) | |
South America | 668 | 9 | 388 | 12 | 37 | 1.35 (1.17, 1.55) | 1.40 (1.18, 1.66) | |
Unknown | 984 | 13 | 441 | 14 | 31 | 1.04 (0.92, 1.18) | 1.02 (0.86, 1.21) | |
Region of residence | <0.0001 | |||||||
London | 3236 | 44 | 1448 | 45 | 31 | Ref | Ref | |
North East | 119 | 2 | 101 | 3 | 46 | 1.90 (1.44, 2.49) | 1.95 (1.44, 2.65) | |
North West | 506 | 7 | 199 | 6 | 28 | 0.88 (0.74, 1.05) | 0.98 (0.81, 1.20) | |
East Midlands | 803 | 11 | 179 | 6 | 18 | 0.50 (0.42, 0.59) | 0.58 (0.48, 0.70) | |
West Midlands | 205 | 3 | 95 | 3 | 32 | 1.04 (0.81, 1.34) | 1.18 (0.89, 1.55) | |
East of England | 364 | 5 | 188 | 6 | 34 | 1.15 (0.96, 1.39) | 1.27 (1.03, 1.57) | |
South East | 471 | 6 | 260 | 8 | 36 | 1.23 (1.05, 1.45) | 1.34 (1.12, 1.62) | |
South West | 306 | 4 | 171 | 5 | 36 | 1.25 (1.03, 1.52) | 1.45 (1.17, 1.80) | |
Yorkshire and the Humber | 772 | 10 | 396 | 12 | 34 | 1.15 (1.00, 1.31) | 1.18 (1.01, 1.38) | |
UK—outside England | 106 | 1 | 32 | 1 | 23 | 0.67 (0.45, 1.01) | 0.63 (0.40, 0.97) | |
Unknown | 494 | 7 | 174 | 5 | 26 | 0.79 (0.66, 0.95) | 0.82 (0.66, 1.00) |
aOR, adjusted Odds Ratio; OR, Odds Ratio.