Seroprevalence of immunity to hepatitis A infection, hepatitis B infection and combined immunity to hepatitis A and B infection, by clinic group and patient characteristics
| Characteristic | HAV IgG | Anti-HBs and combined HAV IgG and anti-HBs | |||||||||
| No of tested HAV | No (%) of positive HAV IgG | 95% CI | P value* | No of tested anti-HBs | No (%) of positive anti-HBs | 95% CI | P value | No (%) of positive HAV IgG anti-HBs | 95% CI | P value | |
| Total | 2577 | 1919 (74.5) | 72.7 to 76.1 | 2551 | 1967 (77.1) | 75.4 to 78.7 | 1562 (61.2) | 59.3 to 63.1 | |||
| Clinic group | |||||||||||
| TDL North London | 450 | 377 (83.8) | 80.1 to 86.9 | <0.001 | 443 | 341 (77.0) | 72.8 to 80.7 | <0.001 | 304 (68.6) | 64.2 to 72.8 | <0.001 |
| Homerton Hospital | 566 | 401 (70.9) | 67.0 to 74.4 | 564 | 443 (78.6) | 75.0 to 81.7 | 341 (60.5) | 56.4 to 64.4 | |||
| St Mary’s Hospital | 467 | 395 (84.6) | 81.0 to 87.6 | 466 | 390 (83.7) | 80.1 to 86.8 | 335 (71.9) | 67.6 to 75.8 | |||
| St Thomas’ Hospital | 643 | 477 (74.2) | 70.7 to 77.4 | 628 | 466 (74.2) | 70.6 to 77.5 | 372 (59.2) | 55.3 to 63.0 | |||
| Leeds Sexual Health | 451 | 269 (59.7) | 55.1 to 64.1 | 450 | 327 (72.7) | 68.4 to 76.6 | 210 (46.7) | 42.1 to 51.3 | |||
| Age group | |||||||||||
| 18–25 | 525 | 320 (61.0) | 56.7 to 65.0 | <0.001 | 515 | 321 (62.3) | 58.1 to 66.4 | <0.001 | 219 (42.5) | 38.3 to 46.8 | <0.001 |
| 26–35 | 979 | 693 (70.8) | 67.9 to 73.5 | 970 | 780 (80.4) | 77.8 to 82.8 | 587 (60.5) | 57.4 to 63.5 | |||
| 36–45 | 600 | 497 (82.8) | 79.6 to 85.6 | 596 | 499 (83.7) | 80.5 to 86.5 | 425 (71.3) | 67.5 to 74.8 | |||
| 46 and over | 473 | 409 (86.5) | 83.1 to 89.3 | 470 | 367 (78.1) | 74.1 to 81.6 | 470 (70.4) | 99.2 to 100.0 | |||
| Region of birth | |||||||||||
| UK | 1363 | 1011 (74.2) | 71.8 to 76.4 | <0.001 | 1348 | 986 (73.2) | 70.7 to 75.4 | <0.001 | 791 (58.7) | 56.0 to 61.3 | 0.10 |
| Africa | 77 | 73 (94.8) | 87.4 to 98.0 | 77 | 64 (83.1) | 73.2 to 89.9 | 61 (79.2) | 68.9 to 86.8 | |||
| Americas | 230 | 174 (75.7) | 69.7 to 80.7 | 226 | 181 (80.1) | 74.4 to 84.8 | 146 (64.6) | 58.2 to 70.5 | |||
| Eastern Mediterranean | 71 | 59 (83.1) | 72.7 to 90.1 | 71 | 54 (76.1) | 65.0 to 84.5 | 46 (64.8) | 53.2 to 74.9 | |||
| Europe | 565 | 382 (67.6) | 63.6 to 71.3 | 560 | 459 (82.0) | 78.6 to 84.9 | 329 (58.8) | 54.6 to 62.8 | |||
| South-East Asia | 47 | 37 (78.7) | 65.1 to 88.0 | 47 | 38 (80.9) | 67.5 to 89.6 | 31 (66.0) | 51.7 to 77.8 | |||
| Western Pacific | 132 | 109 (82.6) | 75.2 to 88.1 | 130 | 113 (86.9) | 80.1 to 91.7 | 95 (73.1) | 64.9 to 80.0 | |||
| Unknown | 92 | 74 (80.4) | 71.2 to 87.3 | 92 | 72 (78.3) | 68.8 to 85.5 | 63 (68.5) | 58.4 to 77.1 | |||
| History of STI in past year | |||||||||||
| No | 1889 | 1359 (71.9) | 69.9 to 73.9 | <0.001 | 1867 | 1392 (74.6) | 72.5 to 76.5 | <0.001 | 1081 (57.9) | 55.6 to 60.1 | <0.001 |
| Yes | 688 | 560 (81.4) | 78.3 to 84.1 | 684 | 575 (84.1) | 81.1 to 86.6 | 481 (70.3) | 66.8 to 73.6 | |||
| HIV status | |||||||||||
| Negative | 2228 | 1609 (72.2) | 70.3 to 74.0 | <0.001 | 2202 | 1671 (75.9) | 74.1 to 77.6 | <0.001 | 1295 (58.8) | 56.7 to 60.8 | <0.001 |
| Positive | 349 | 310 (88.8) | 85.1 to 91.7 | 349 | 296 (84.8) | 80.7 to 88.2 | 267 (76.5) | 71.8 to 80.6 | |||
*P values from χ2 tests.
HAV, hepatitis A virus; STI, sexually transmitted infection; TDL, The Doctor’s Laboratory.