Characteristics of three vaginal flora patterns assessed Gram stain among pregnant women*,**
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Cited by (210)
Giants in Obstetrics and Gynecology Series: a profile of Robert L. Goldenberg, MD
2021, American Journal of Obstetrics and GynecologyGardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice
2021, American Journal of Obstetrics and GynecologyIdentification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis
2019, Journal of Biological ChemistryCitation Excerpt :We also assessed the ability of NanH2 and NanH3 to cleave α2-3–linked sialic acids on the capsular polysaccharide of the vaginal bacterium group B Streptococcus (GBS). GBS is an important potential pathogen during pregnancy (49) and is often found colonizing the vagina in women with high Nugent scores (50), a method of laboratory diagnosis for BV (23). As with the other sialoglycan substrates, both NanH2 and NanH3 cleaved Neu5Ac from the GBS capsule (Fig. 3D).
- *
Members of the Vaginal Infections and Prematurity Study Group and their affiliations are listed at the end of the article.
- **
Supported by contracts HD-3-2832, HD-3-2833, HD-3-2834, HD-3-2835, HD-3-2836, and AI-4-2532 from the National Institute of Child Health and Human Development and the National Institute of Allergy and Infectious Diseases.
- a
From the Department of Obstetrics and Gynecology, University of Washington
- b
From the Department of Epidemiology, University of Washington
- c
National Institute of Child Health and Human Development, University of Colorado Health Science Center.
- d
Department of Obstetrics and Gynecology, University of Colorado Health Science Center.