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Cooled lignocaine gel: Does it reduce urethral discomfort during instillation?

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Abstract

Introduction: Topical urethral analgesia with 2%lignocaine gel for office procedures is anaccepted practice in contemporary urology.However, instillation of 2% lignocaine gelinto the urethra is associated with discomfort insome patients.Material and Methods: Forty consentingmen reporting for cystoscopy under localanesthesia were randomized to receive 10 ml of2% lignocaine hydrochloride gel at 4 °Cand 22 °C. After instillation of the gel thepatients were immediately asked to score thepain using a nongraphical visual analogue scale.Results: The pain scores were analyzedusing the paired Student's t-test. There wassignificant reduction in pain scores in thegroup receiving gel at 4 °C compared with thegroup at 22 °C (P < 0.05).Conclusion: Refrigerating the gel to 4 °Ccan significantly reduce the initial discomfortassociated with instillation of 2% lignocainehydrochloride into the male urethra.

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Goel, R., Aron, M. Cooled lignocaine gel: Does it reduce urethral discomfort during instillation?. Int Urol Nephrol 35, 375–377 (2003). https://doi.org/10.1023/B:UROL.0000022910.28815.30

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  • DOI: https://doi.org/10.1023/B:UROL.0000022910.28815.30

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