General Obstetrics and Gynecology GynecologyAccuracy of detection of trichomonas vaginalis organisms on a liquid-based papanicolaou smear☆,☆☆
Section snippets
Material and Methods
From June 2001 to October 2001, after the protocol was approved by the Institutional Review Board of University Hospitals of Cleveland, 203 consecutive patients seen in an urban women's health center who required a Pap smear also had a culture taken for T vaginalis using the In Pouch TV (Biomed Diagnostics). After giving consent, patients first had a Pap smear with the standard liquid-based method used in our center, followed by a cervicovaginal swab for T vaginalis. If the patient was
Results
Demographic data are shown in Table I.Race White 8 (4%) African American 195 (96%) Pregnant 55 (27%) Gravidity* 2 (0-10) Parity* 1 (0-8) Age 22 (18-67) Gestational age* 11 (6-34)† Presence of symptoms 85 (42%) Previous STDs by history 124 (61%) *Median (range). †In weeks.
Comment
Although the presence of T vaginalis on conventional Pap smear is still reported as an incidental finding by the pathologist giving it low sensitivity, the high specificity of the test improves the diagnosis of this disease in patients who otherwise were asymptomatic and did not have a wet mount at their office visit. In asymptomatic patients, the liquid-based Pap smear was able to detect the presence of the organism in 9.6% more patients who otherwise would not have had a test performed.
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Cited by (60)
Prevalence and spatial heterogeneity of Trichomonas vaginalis infection among the female population and association with climate in Guangxi Zhuang autonomous region, Southern China
2022, Acta TropicaCitation Excerpt :Hence, asymptomatic TVI cases are likely to be found in this study. Liquid-based cytology features satisfactory sensitivity and specificity in the diagnosis of TV (Lara-Torre and Pinkerton, 2003). In the present study, the infection rate was lower than those in previous studies in China (Luo et al., 2016; Su et al., 2016), which may be related to the inexperience in identifying T. vaginalis through liquid-based cytology.
Risk of high-risk human papillomavirus infection and cervical precancerous lesions with past or current trichomonas infection: a pooled analysis of 25,054 women in rural China
2018, Journal of Clinical VirologyCitation Excerpt :Previous studies that evaluated the association between TV infection on HPV persistence and CIN+ had inconsistent results. Several studies reported no causal role for TV on cervical cancer [36,37]. A frequently cited meta-analysis of 24 studies showed an increased relative risk for cervical cancer with TV infection; [13] however, this analysis was powered by only two cohort studies (Gram 1992; Zhang 1991).
Cycloartenol triterpenoid saponins from Cimicifuga simplex (Ranunculaceae) and their biological effects
2015, Chinese Journal of Natural MedicinesTesting and treatment for sexually transmitted infections in adolescents-what's new?
2014, Journal of Pediatric and Adolescent GynecologyCitation Excerpt :Wet mount is currently the most commonly used testing methodology for Trichomonas vaginalis (TV) but suffers from poor sensitivity (60%-70%).40–42 PAP smear has been found to have a sensitivity similar to wet mount at 60%, which is improved when liquid media are used.43 TV testing methodologies clinically available are culture, POCTs, and NAAT tests (Amplicor PCR and APTIMA-Gen-Probe).
Trichomoniasis: The "neglected" sexually transmitted disease
2013, Infectious Disease Clinics of North AmericaCitation Excerpt :Cultures may be inoculated with a variety of specimen types from men or women, including genital secretions, semen, or urine. Neither traditional nor liquid-based Papanicolaou tests (Pap smears) are considered appropriate diagnostic or screening tests for trichomoniasis because of their poor sensitivity.20,21 However, the specificity of liquid-based cytology for T vaginalis is high.22,23
Urethritis, Vulvovaginitis, and Cervicitis
2012, Principles and Practice of Pediatric Infectious Diseases, Fourth Edition
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Supported by departmental funds.
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Reprint requests: Eduardo Lara-Torre, MD, Department of Obstetrics and Gynecology, University of Louisville, 550 S Jackson St, Louisville, KY 40202. E-mail: [email protected]