Serologic screening for herpes simplex virus among university students: a pilot study

J Am Coll Health. 2008 Nov-Dec;57(3):291-6. doi: 10.3200/JACH.57.3.291-296.

Abstract

Objective: The authors examined the feasibility of conducting serologic testing for the herpes simplex virus 2 (HSV-2) among university students and assessed the psychosocial impact of an HSV-2 diagnosis.

Methods: The authors recruited a convenience sample of 100 students (aged 18-39 years) without a history of genital herpes from 1 university between September 2004 and March 2006. Participants received HSV-2 antibody testing by Focus ELISA and Western Blot assays and completed a questionnaire that addressed psychological functioning. Twenty-eight participants completed the questionnaire again at a 3-month follow-up visit.

Results: The study revealed (1) low test-reliability in the student population, (2) that positive test results may cause a decline in psychological well-being, and (3) that substantial resources are required to support students with positive HSV-2 results.

Conclusions: Test performance, psychological impact, and availability of resources for counseling students with positive diagnoses should be considered before implementing HSV testing programs.

MeSH terms

  • Adolescent
  • Adult
  • Blotting, Western
  • Enzyme-Linked Immunosorbent Assay
  • Feasibility Studies
  • Female
  • Focus Groups
  • Health Behavior
  • Health Care Surveys
  • Herpesviridae Infections / epidemiology*
  • Humans
  • Male
  • Mass Screening / statistics & numerical data*
  • Simplexvirus*
  • Students / statistics & numerical data*
  • Surveys and Questionnaires
  • United States / epidemiology
  • Universities / statistics & numerical data*
  • Young Adult