Emergence of high level azithromycin-resistant Neisseria gonorrhoeae strain isolated in Argentina

Sex Transm Dis. 2009 Dec;36(12):787-8. doi: 10.1097/OLQ.0b013e3181b61bb1.

Abstract

One Neisseria gonorrhoeae strains highly resistant to azithromycin AzHLR (MIC >2048 mg/L) was isolated in Argentina in 2001 and it has been characterized by N. gonorrhoeae multiantigen sequence typing (NG-MAST) as ST696, suggesting a different event to other isolates in Europe. Neither, mtrR mutations or presence of mef gene were detected.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Argentina / epidemiology
  • Azithromycin / pharmacology*
  • Bacterial Proteins / genetics
  • Drug Resistance, Bacterial* / genetics
  • Gonorrhea / epidemiology*
  • Gonorrhea / microbiology*
  • Humans
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae / classification
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / isolation & purification
  • Sequence Analysis, DNA

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Azithromycin