Abstract
Neisseria gonorrhoeae multi-antigen sequence typing technique demonstrated multiple sexual transmission networks in Ontario, Canada. Isolates with novel sequences had higher odds of originating in Toronto but had no association with heightened population-level quinolone exposure. Neisseria gonorrhoeae multi-antigen sequence typing technique can be a useful tool for investigation of multidrug-resistant N. gonorrhoeae emergence in North America.
MeSH terms
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Adolescent
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Adult
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Aged
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Ambulatory Care Facilities
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Anti-Bacterial Agents / pharmacology*
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DNA, Bacterial / genetics
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Drug Resistance, Multiple, Bacterial / drug effects*
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Female
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Gonorrhea / epidemiology
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Gonorrhea / microbiology*
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Gonorrhea / transmission
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Homosexuality, Male
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Humans
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Logistic Models
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Molecular Typing / methods
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Neisseria gonorrhoeae / classification*
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Neisseria gonorrhoeae / drug effects
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Neisseria gonorrhoeae / genetics
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Ontario / epidemiology
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Quinolones / pharmacology*
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Sexual Behavior
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Young Adult
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Quinolones