Emergence of fluoroquinolone resistance in Neisseria gonorrhoeae isolates from four clinics in three regions of Kenya

Sex Transm Dis. 2012 May;39(5):332-4. doi: 10.1097/OLQ.0b013e318248a85f.

Abstract

We have recently reported high levels of fluoroquinolone resistance in a single region of Kenya. In this article, we report high prevalence of fluoroquinolone resistance (53.2%) in Neisseria gonorrhoeae isolates from 4 clinics in 3 additional regions of Kenya. These findings highlight the need to change first-line treatment in these settings and the need to evaluate empirical management guidelines for treatment of gonococcal infection in Kenya.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Drug Resistance, Bacterial*
  • Female
  • Fluoroquinolones / administration & dosage*
  • Fluoroquinolones / pharmacology
  • Gonorrhea / drug therapy*
  • Gonorrhea / prevention & control
  • Gonorrhea / transmission
  • Humans
  • Kenya / epidemiology
  • Male
  • Mass Screening
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae / drug effects
  • Neisseria gonorrhoeae / isolation & purification*
  • Prevalence
  • Sentinel Surveillance

Substances

  • Fluoroquinolones