Vaginal swabs are the optimal specimen for detection of genital Chlamydia trachomatis or Neisseria gonorrhoeae using the Cobas 4800 CT/NG test

Barbara Van Der Pol; Stephanie N Taylor; Oliver Liesenfeld; James A Williams; Edward W Hook 3rd

doi:10.1097/OLQ.0b013e3182717833

Vaginal swabs are the optimal specimen for detection of genital Chlamydia trachomatis or Neisseria gonorrhoeae using the Cobas 4800 CT/NG test

Sex Transm Dis. 2013 Mar;40(3):247-50. doi: 10.1097/OLQ.0b013e3182717833.

Authors

Barbara Van Der Pol¹, Stephanie N Taylor, Oliver Liesenfeld, James A Williams, Edward W Hook 3rd

Affiliation

¹ Indiana University School of Public Health, Bloomington, IN 47405, USA. bvanderp@indiana.edu

PMID: 23407470
DOI: 10.1097/OLQ.0b013e3182717833

Abstract

Performance characteristics of the Cobas 4800 CT/NG assay were estimated for vaginal swab samples from more than 4000 women. Vaginal samples identified 92.9% and 98.5% of Chlamydia and Gonorrhea infections, respectively, which was more than any other single specimen type (endocervical swabs or urine) regardless of collection method (clinician collected or self-obtained).

Publication types

Comparative Study
Multicenter Study
Randomized Controlled Trial

MeSH terms

Chlamydia Infections / diagnosis*
Chlamydia Infections / urine
Chlamydia trachomatis / isolation & purification*
Female
Gonorrhea / diagnosis*
Gonorrhea / urine
Humans
Molecular Diagnostic Techniques / methods
Neisseria gonorrhoeae / isolation & purification*
Nucleic Acid Amplification Techniques / methods
Patient Preference
Sensitivity and Specificity
Specimen Handling / methods
Urine / microbiology*
Vagina / microbiology*
Vaginal Smears*