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Helicase-primase inhibitor pritelivir for HSV-2 infection.
Wald A, Corey L, Timmler B, Magaret A, Warren T, Tyring S, Johnston C, Kriesel J, Fife K, Galitz L, Stoelben S, Huang ML, Selke S, Stobernack HP, Ruebsamen-Schaeff H, Birkmann A. Wald A, et al. Among authors: ruebsamen schaeff h. N Engl J Med. 2014 Jan 16;370(3):201-10. doi: 10.1056/NEJMoa1301150. N Engl J Med. 2014. PMID: 24428466 Free article. Clinical Trial.
Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections.
Birkmann A, Bonsmann S, Kropeit D, Pfaff T, Rangaraju M, Sumner M, Timmler B, Zimmermann H, Buschmann H, Ruebsamen-Schaeff H. Birkmann A, et al. Among authors: ruebsamen schaeff h. J Med Chem. 2022 Oct 27;65(20):13614-13628. doi: 10.1021/acs.jmedchem.2c00668. Epub 2022 Oct 6. J Med Chem. 2022. PMID: 36202389 Free PMC article.
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
Lischka P, Hewlett G, Wunberg T, Baumeister J, Paulsen D, Goldner T, Ruebsamen-Schaeff H, Zimmermann H. Lischka P, et al. Among authors: ruebsamen schaeff h. Antimicrob Agents Chemother. 2010 Mar;54(3):1290-7. doi: 10.1128/AAC.01596-09. Epub 2010 Jan 4. Antimicrob Agents Chemother. 2010. PMID: 20047911 Free PMC article.
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences: A Randomized Clinical Trial.
Wald A, Timmler B, Magaret A, Warren T, Tyring S, Johnston C, Fife K, Selke S, Huang ML, Stobernack HP, Zimmermann H, Corey L, Birkmann A, Ruebsamen-Schaeff H. Wald A, et al. Among authors: ruebsamen schaeff h. JAMA. 2016 Dec 20;316(23):2495-2503. doi: 10.1001/jama.2016.18189. JAMA. 2016. PMID: 27997653 Clinical Trial.
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