Periostin is considered to be a matricellular protein with expression typically confined to
cells of mesenchymal origin. Here, by using in situ hybridization, we show that periostin is …

Background Habitual cigarette smoking is associated with chronic mucus hypersecretion,
but the relationship between mucus abnormalities and airflow obstruction in smokers is …

Rationale: Airway mucus plugs, composed of mucin glycoproteins mixed with plasma
proteins, are an important cause of airway obstruction in acute severe asthma, and they are …

Rapid technology introduction and expansion may change the paradigm for improving
provider knowledge and practice. Although new, the developments are promising for HIV …

In Vietnam, chest radiography (CXR) is used to refer people for GeneXpert (Xpert) testing to
diagnose tuberculosis (TB), demonstrating high yield for TB but a wide range of CXR …

Rationale: Acute asthma exacerbations, precipitated by viral infections, are a significant
cause of morbidity, but not all patients with asthma are equally susceptible. Objectives: To …

Bronchoscopy with bronchial biopsies allows sampling of airway tissue in prospective
clinical studies and is increasingly applied for the study of airway inflammation and …

Background Mucociliary clearance is impaired in chronic rhinosinusitis (CRS). Clearance of
sinonasal secretions is influenced by its rheological properties. The purpose of this study …

SETTING: TB infection (TBI) is diagnosed using the technique-dependent tuberculin skin test
(TST) or costly, more accurate interferon-gamma release assays. The TST (10 mm) …

Multidrug-resistant tuberculosis (MDR-TB) is a particular threat to the populations of
resource-limited countries. Although inadequate treatment of TB has been identified as a …