Role of FKS mutations in Candida glabrata: MIC values, echinocandin resistance, and multidrug resistance

CD Pham, N Iqbal, CB Bolden… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Candida glabrata is the second leading cause of candidemia in US hospitals. Current
guidelines suggest that an echinocandin be used as the primary therapy for the treatment of …

[HTML][HTML] The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi… - Nature …, 2017 - nature.com
As genomics advances reveal the cancer gene landscape, a daunting task is to understand
how these genes contribute to dysregulated oncogenic pathways. Integration of cancer …

Epidemiology and Risk Factors for Echinocandin Nonsusceptible Candida glabrata Bloodstream Infections: Data From a Large Multisite Population-Based …

S Vallabhaneni, AA Cleveland… - Open forum …, 2015 - academic.oup.com
Background. Echinocandins are first-line treatment for Candida glabrata candidemia.
Echinocandin resistance is concerning due to limited remaining treatment options. We used …

[HTML][HTML] Malignant Transformation of Hymenolepis nana in a Human Host

A Muehlenbachs, J Bhatnagar… - … England Journal of …, 2015 - Mass Medical Soc
Neoplasms occur naturally in invertebrates but are not known to develop in tapeworms. We
observed nests of monomorphic, undifferentiated cells in samples from lymph-node and …

Molecular mechanisms of fluconazole resistance in Candida parapsilosis isolates from a US surveillance system

NT Grossman, CD Pham, AA Cleveland… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Candida parapsilosis is the second or third most common cause of candidemia in many
countries. The Infectious Diseases Society of America recommends fluconazole as the …

Expanding US Laboratory capacity for Neisseria gonorrhoeae antimicrobial susceptibility testing and whole-genome sequencing through the CDC's antibiotic …

EN Kersh, CD Pham, JR Papp, R Myers… - Journal of Clinical …, 2020 - Am Soc Microbiol
ABSTRACT US gonorrhea rates are rising, and antibiotic-resistant Neisseria gonorrhoeae
(AR-Ng) is an urgent public health threat. Since implementation of nucleic acid amplification …

[HTML][HTML] Passive surveillance for azole-resistant Aspergillus fumigatus, United States, 2011–2013

CD Pham, E Reiss, F Hagen, JF Meis… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
Emergence of Aspergillus fumigatus strains containing mutations that lead to azole
resistance has become a serious public health threat in many countries. Nucleotide …

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus

CE Rouquette-Loughlin, JL Reimche, JT Balthazar… - MBio, 2018 - Am Soc Microbiol
Recent reports suggest that mosaic-like sequences within the mtr (m ultiple t ransferable r
esistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal …

[HTML][HTML] Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data

KM Gernert, S Seby, MW Schmerer, JC Thomas… - The Lancet …, 2020 - thelancet.com
Background The number of cases of gonorrhoea in the USA and worldwide caused by
Neisseria gonorrhoeae is increasing (555 608 reported US cases in 2017, and 87 million …

[HTML][HTML] Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the …

ACP Souto, LX Bonfietti, K Ferreira-Paim… - PLoS neglected …, 2016 - journals.plos.org
Cryptococcus neoformans and Cryptococcus gattii are responsible globally for almost one
million cryptococcosis cases yearly, mostly in immunocompromised patients, such as those …