User profiles for "author:Clémence Leyrat"
Clémence LeyratLondon School of Hygiene and Tropical Medicine Verified email at lshtm.ac.uk Cited by 1700 |
[HTML][HTML] Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study
Abstract Background Cluster randomised trials (CRTs) are commonly analysed using mixed-
effects models or generalised estimating equations (GEEs). However, these analyses do not …
effects models or generalised estimating equations (GEEs). However, these analyses do not …
[HTML][HTML] Open science saves lives: lessons from the COVID-19 pandemic
In the last decade Open Science principles have been successfully advocated for and are
being slowly adopted in different research communities. In response to the COVID-19 …
being slowly adopted in different research communities. In response to the COVID-19 …
Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial
MJ Smith, MA Mansournia, C Maringe… - Statistics in …, 2022 - Wiley Online Library
The main purpose of many medical studies is to estimate the effects of a treatment or
exposure on an outcome. However, it is not always possible to randomize the study …
exposure on an outcome. However, it is not always possible to randomize the study …
Propensity score analysis with partially observed covariates: how should multiple imputation be used?
Inverse probability of treatment weighting is a popular propensity score-based approach to
estimate marginal treatment effects in observational studies at risk of confounding bias. A …
estimate marginal treatment effects in observational studies at risk of confounding bias. A …
Cluster randomized trials with a small number of clusters: which analyses should be used?
Abstract Background Cluster randomized trials (CRTs) are increasingly used to assess the
effectiveness of health interventions. Three main analysis approaches are: cluster-level …
effectiveness of health interventions. Three main analysis approaches are: cluster-level …
Quality of reporting of pilot and feasibility cluster randomised trials: a systematic review
CL Chan, C Leyrat, SM Eldridge - BMJ open, 2017 - bmjopen.bmj.com
Objectives To systematically review the quality of reporting of pilot and feasibility of cluster
randomised trials (CRTs). In particular, to assess (1) the number of pilot CRTs conducted …
randomised trials (CRTs). In particular, to assess (1) the number of pilot CRTs conducted …
Reflection on modern methods: trial emulation in the presence of immortal-time bias. Assessing the benefit of major surgery for elderly lung cancer patients using …
C Maringe, S Benitez Majano… - International journal …, 2020 - academic.oup.com
Acquiring real-world evidence is crucial to support health policy, but observational studies
are prone to serious biases. An approach was recently proposed to overcome confounding …
are prone to serious biases. An approach was recently proposed to overcome confounding …
[HTML][HTML] G-computation, propensity score-based methods, and targeted maximum likelihood estimator for causal inference with different covariates sets: a comparative …
Controlling for confounding bias is crucial in causal inference. Distinct methods are currently
employed to mitigate the effects of confounding bias. Each requires the introduction of a set …
employed to mitigate the effects of confounding bias. Each requires the introduction of a set …
MatchThem:: matching and weighting after multiple imputation
Balancing the distributions of the confounders across the exposure levels in an
observational study through matching or weighting is an accepted method to control for …
observational study through matching or weighting is an accepted method to control for …
Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study
Objective To determine if trimethoprim use for urinary tract infection (UTI) is associated with
an increased risk of acute kidney injury, hyperkalaemia, or sudden death in the general …
an increased risk of acute kidney injury, hyperkalaemia, or sudden death in the general …