Peripheral nerve injuries that induce gaps larger than 1–2cm require bridging strategies for
repair. Autologous nerve grafts are still the gold standard for such interventions, although …

Background Whereas 40 million individuals are estimated to be infected with HIV worldwide,
nearly 400 million people are chronic HBV carriers [10]. HBV and HIV are endemic in the …

Our long-term goal is to develop an artificial implant as a conduit for axonal regeneration
after peripheral nerve injury. In this study, biodegradable, aligned poly-ε-caprolactone (PCL) …

British HIV Association Guidelines for the treatment of HIV-1-infected adults with
antiretroviral therapy 2008 British HIV Association Guidelines for the treatment of HIV-1-infected …

After central nervous system (CNS) injury, inhibitory factors in the lesion scar and poor axon
growth potential prevent axon regeneration. Microtubule stabilization reduces scarring and …

Spinal cord injury triggers irreversible loss of motor and sensory functions. Numerous
strategies aiming at repairing the injured spinal cord have been studied. Among them, the …

Nerve injury leads to the release of a number of cytokines which have been shown to play
an important role in cellular activation after peripheral nerve injury. The members of the …

The goal of this study was the development of a bioartificial nerve guide to induce axonal
regeneration in the peripheral nervous system (PNS). In this in vitro study, the ability of a …

Therapeutic benefits of autologous nerve grafting in repair of peripheral nerve lesions have
not been reached using any alternative nerve guide. Nevertheless, issues of co-morbidity …

The use of bioengineered nerve guides as alternatives for autologous nerve transplantation
(ANT) is a promising strategy for the repair of peripheral nerve defects. In the present …