Maternal or infant antiretroviral drugs to reduce HIV-1 transmission

CS Chasela, MG Hudgens, DJ Jamieson… - Obstetrical & …, 2010 - journals.lww.com
The findings of a number of observational or uncontrolled studies suggested that initiation of
an antiretroviral regimen during the antenatal period and continuation postpartum markedly …

QT effects of bedaquiline, delamanid, or both in patients with rifampicin-resistant tuberculosis: a phase 2, open-label, randomised, controlled trial

KE Dooley, SL Rosenkranz, F Conradie… - The Lancet Infectious …, 2021 - thelancet.com
Background Bedaquiline and delamanid are the first drugs of new classes registered for
tuberculosis treatment in 40 years. Each can prolong the QTc interval, with maximum effects …

Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial

DJ Jamieson, CS Chasela, MG Hudgens, CC King… - The Lancet, 2012 - thelancet.com
Background In resource-limited settings where no safe alternative to breastfeeding exists,
WHO recommends that antiretroviral prophylaxis be given to either HIV-infected mothers or …

Association of HIV-1 envelope-specific breast milk IgA responses with reduced risk of postnatal mother-to-child transmission of HIV-1

J Pollara, E McGuire, GG Fouda, W Rountree… - Journal of …, 2015 - Am Soc Microbiol
Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding
is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding …

Maternal and breastmilk viral load: impacts of adherence on peripartum HIV infections averted—the Breastfeeding, Antiretrovirals, and Nutrition Study

NL Davis, WC Miller, MG Hudgens… - JAIDS Journal of …, 2016 - journals.lww.com
Background: Antiretroviral (ARV) interventions are used to reduce HIV viral replication and
prevent mother-to-child transmission. Viral suppression relies on adherence to ARVs …

[HTML][HTML] Supporting Option B+ scale up and strengthening the prevention of mother-to-child transmission cascade in central Malawi: results from a serial cross …

ME Herce, T Mtande, F Chimbwandira, I Mofolo… - BMC infectious …, 2015 - Springer
Abstract Background We established Safeguard the Family (STF) to support Ministry of
Health (MoH) scale-up of universal antiretroviral therapy (ART) for HIV-infected pregnant …

Measures of viral load using Abbott RealTime HIV-1 Assay on venous and fingerstick dried blood spots from provider-collected specimens in Malawian District …

SE Rutstein, D Kamwendo, L Lugali… - Journal of Clinical …, 2014 - Elsevier
Background Viral suppression is a key indicator of antiretroviral therapy (ART) response
among HIV-infected patients. Dried blood spots (DBS) are an appealing alternative to …

Occurrence and distribution of nonfalciparum malaria parasite species among adolescents and adults in Malawi

A Gumbo, HM Topazian, A Mwanza… - The Journal of …, 2022 - academic.oup.com
Background Plasmodium falciparum malaria dominates throughout sub-Saharan Africa, but
the prevalence of Plasmodium malariae, Plasmodium ovale spp., and Plasmodium vivax …

[HTML][HTML] Asymptomatic Plasmodium falciparum malaria prevalence among adolescents and adults in Malawi, 2015–2016

HM Topazian, A Gumbo, S Puerto-Meredith, R Njiko… - Scientific reports, 2020 - nature.com
Malaria remains a significant cause of morbidity and mortality in Malawi, with an estimated
18–19% prevalence of Plasmodium falciparum in children 2–10 years in 2015–2016. While …

Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children

PT McGann, AM Williams, G Ellis… - Blood …, 2018 - ashpublications.org
Abstract In sub-Saharan Africa, inherited causes of anemia are common, but data are limited
regarding the geographical prevalence and coinheritance of these conditions and their …