[HTML][HTML] Biliary sludge as a cause of acute pancreatitis

SP Lee, JF Nicholls, HZ Park - New England Journal of Medicine, 1992 - Mass Medical Soc
Background. In about 20 to 40 percent of cases of acute pancreatitis, no cause can be found,
and these are labeled idiopathic. In this study, we sought to determine the frequency with …

Origin and fate of biliary sludge

SP Lee, K Maher, JF Nicholls - Gastroenterology, 1988 - Elsevier
Biliary sludge is a collection of mucus, calcium bilirubinate, and cholesterol crystals that is
usually recognized by characteristic echoes on ultrasonography. Its pathogenesis, clinical …

An epilepsy mutation in the β1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin

PT Lucas, LS Meadows, J Nicholls, DS Ragsdale - Epilepsy research, 2005 - Elsevier
The antiepileptic drug phenytoin inhibits voltage-gated sodium channels. Phenytoin block is
enhanced at depolarized membrane potentials and during high frequency channel …

[HTML][HTML] Scaling up screening and treatment for elimination of hepatitis C among men who have sex with men in the era of HIV pre-exposure prophylaxis

L Macgregor, M Desai, NK Martin, J Nicholls… - …, 2020 - thelancet.com
Background Routine HIV pre-exposure prophylaxis (PrEP) and HIV care appointments
provide opportunities for screening men who have sex with men (MSM) for hepatitis C virus …

Evidence of changing sexual behaviours and clinical attendance patterns, alongside increasing diagnoses of STIs in MSM and TPSM

L MacGregor, N Speare, J Nicholls… - Sexually transmitted …, 2021 - sti.bmj.com
Background Due to rising numbers of STI diagnosis and increasing prevalence of
antimicrobial resistance, we explored trends in STI testing frequency and diagnoses …

Incidence of hypertension and blood pressure changes in persons with HIV at high risk for cardiovascular disease switching from boosted protease inhibitors to …

A Sempere, L Assoumou… - Clinical Infectious …, 2023 - academic.oup.com
Background Integrase inhibitors have been recently linked to a higher risk for hypertension.
In NEAT022 randomized trial, virologically suppressed persons with HIV (PWH) with high …

The effects of old age and distraction on the assessment of prospective memory in a simulated naturalistic environment

RG Knight, J Nicholls, N Titov - International Psychogeriatrics, 2008 - cambridge.org
Background: The ability to remember to complete future intentions, prospective memory,
often begins to fail in old age. The aim of the present study was to examine the sensitivity of …

Cross-sectional study to evaluate Trichomonas vaginalis positivity in women tested for Neisseria gonorrhoeae and Chlamydia trachomatis, attending genitourinary …

JE Nicholls, KME Turner, P North, R Ferguson… - Sexually Transmitted …, 2018 - sti.bmj.com
Background Highly sensitive, commercial nucleic acid amplification tests (NAAT) for
Trichomonas vaginalis have only recently been recommended for use in the UK. While …

Preventing unintentional childhood injury at home: Injury circumstances and interventions

JC Simpson, J Nicholls - International journal of injury control and …, 2012 - Taylor & Francis
New Zealand's (NZ) preschoolers carry the greatest injury burden among children aged 0–
14 years. These injuries commonly occur at home. To identify how NZ addresses child injury …

Diffusion of charged ions in mucus gel: effect of net charge

SP Lee, JF Nicholls - Biorheology, 1987 - content.iospress.com
The interposition of a neutral starch gel greatly retarded bulk ionic movement by free flow. A
mucus (charged) gel preparation of identical concentration and thickness further retarded …