Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
A Bellacosa, D De Feo, AK Godwin… - … journal of cancer, 1995 - Wiley Online Library
The AKT2 gene is one of the human homologues of v‐akt, the transduced oncogene of the
AKT8 virus, which induces lymphomas in mice. In previous studies, AKT2, which codes for a …
AKT8 virus, which induces lymphomas in mice. In previous studies, AKT2, which codes for a …
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
JQ Cheng, B Ruggeri, WM Klein… - Proceedings of the …, 1996 - National Acad Sciences
We previously demonstrated that the putative oncogene AKT2 is amplified and
overexpressed in some human ovarian carcinomas. We have now identified amplification of …
overexpressed in some human ovarian carcinomas. We have now identified amplification of …
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.
JQ Cheng, AK Godwin, A Bellacosa… - Proceedings of the …, 1992 - National Acad Sciences
We isolated cDNA clones containing the entire coding region of the putative oncogene
AKT2. Sequence analysis and in vitro translation demonstrated that AKT2 encodes a 56-kDa …
AKT2. Sequence analysis and in vitro translation demonstrated that AKT2 encodes a 56-kDa …
High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.
AB Bianchi, SI Mitsunaga, JQ Cheng… - Proceedings of the …, 1995 - National Acad Sciences
Malignant mesotheliomas (MMs) are aggressive tumors that develop most frequently in the
pleura of patients exposed to asbestos. In contrast to many other cancers, relatively few …
pleura of patients exposed to asbestos. In contrast to many other cancers, relatively few …
p16 Alterations and Deletion Mapping of 9p21–p22 in Malignant Mesothelioma
JQ Cheng, SC Jhanwar, WM Klein, DW Bell, WC Lee… - Cancer research, 1994 - AACR
To determine whether p16 is altered in human malignant mesothelioma (MM), molecular
analysis of multiple 9p loci was performed on 40 cell lines and 23 primary tumors from 42 …
analysis of multiple 9p loci was performed on 40 cell lines and 23 primary tumors from 42 …
[HTML][HTML] MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
CZ Zhang, JX Zhang, AL Zhang, ZD Shi, L Han, ZF Jia… - Molecular cancer, 2010 - Springer
Abstract Background MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in
various types of human malignancy including glioblastoma. Recent studies have reported …
various types of human malignancy including glioblastoma. Recent studies have reported …
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
BA Ruggeri, L Huang, M Wood… - … in cooperation with …, 1998 - Wiley Online Library
AKT2, an oncogene encoding a protein serine‐threonine kinase implicated in
phosphatidylinositol‐3‐OH kinase signaling, is amplified in some human ovarian and …
phosphatidylinositol‐3‐OH kinase signaling, is amplified in some human ovarian and …
Advances in the analysis of chromosome alterations in human lung carcinomas
JR Testa, Z Liu, M Feder, DW Bell, B Balsara… - Cancer genetics and …, 1997 - Elsevier
A review of chromosomal analyses of human lung carcinomas is presented. Karyotypic
studies have revealed multiple cytogenetic changes in most small cell lung carcinomas …
studies have revealed multiple cytogenetic changes in most small cell lung carcinomas …
Emergence, circulation, and spatiotemporal phylogenetic analysis of coxsackievirus a6-and coxsackievirus a10-associated hand, foot, and mouth disease infections …
YQ He, L Chen, WB Xu, H Yang, HZ Wang… - Journal of Clinical …, 2013 - Am Soc Microbiol
Sporadic hand, foot, and mouth disease (HFMD) outbreaks and other infectious diseases in
recent years have frequently been associated with certain human enterovirus (HEV) …
recent years have frequently been associated with certain human enterovirus (HEV) …
MicroRNA‐21 expression is regulated by β‐catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK
L Han, X Yue, X Zhou, FM Lan, G You… - CNS neuroscience & …, 2012 - Wiley Online Library
SUMMARY Aims MicroRNA‐21 (miR‐21) expression is increased in many types of human
malignancy, including glioma. Recent studies report that miR‐21 regulates cell invasion by …
malignancy, including glioma. Recent studies report that miR‐21 regulates cell invasion by …