Background Paromomycin-based topical treatments were shown to be effective in curing
cutaneous leishmaniasis (CL) lesions caused by Leishmania major in Tunisia. Cure rates of …

The recently enriched genomic history of Indigenous groups in the Americas is still meager
concerning continental Central America. Here, we report ten pre-Hispanic (plus two early …

The Isthmus of Panama–the narrow neck of land connecting the northern and southern
American landmasses–was an obligatory corridor for the Paleo-Indians as they moved into …

Twenty years have passed since the emergence of hantavirus zoonosis in Panama at the
beginning of this millennium. We provide an overview of epidemiological surveillance of …

Rocky Mountain spotted fever (RMSF) is a tick-borne infection caused by Rickettsia rickettsii.
We report a cluster of fatal cases of RMSF in 2007 in Panama, involving a pregnant woman …

We report an epidemiologic analysis of 4,210 cases of infection with severe acute
respiratory syndrome coronavirus 2 and genetic analysis of 313 new near-complete virus …

Introduction Progress with the treatment of cutaneous leishmaniasis (CL) has been
hampered by inconsistent methodologies used to assess treatment effects. A sizable …

The Costa Rican pygmy rice rat (Oligoryzomys costaricensis) is the primary reservoir of
Choclo orthohantavirus (CHOV), the causal agent of hantavirus disease, pulmonary …

Background There is scant information on sexually transmitted infection (STI) prevalence
and risk factors among Latin American indigenous populations. We investigated STI …

The first outbreak of hantavirus pulmonary syndrome (HPS) in Central America was
documented on the Azuero peninsula of Panama in late 1999 and 2000. Reverse …