Mesenteric ischaemia may result from a wide range of pathological processes, each
possessing unique clinical features, diagnostic difficulties, management strategies and …

This guideline describes the approach and expertise needed for the genetic evaluation of
cardiomyopathy. First published in 2009 by the Heart Failure Society of America (HFSA), the …

Carriers of germline mutations in the TP53 gene, encoding the cell-cycle regulator and
tumour suppressor p53, have a markedly increased risk of cancer-related morbidity and …

Abstract Treatment with immune checkpoint blockade (ICB) has revolutionized cancer
therapy. Until now, predictive biomarkers,,,,,,,,–and strategies to augment clinical response …

Interindividual gene copy-number variation (CNV) of complement component C4 and its
associated polymorphisms in gene size (long and short) and protein isotypes (C4A and …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of genes that
share miRNA target sequences. To examine the physiologic effects of an individual miRNA …

The complete DNA sequence was determined of a pathogenic British isolate of equine
herpesvirus-1, a respiratory virus which can cause abortion and neurological disease. The …

PurposeThe major cause of death in aggressive lymphoma is relapse or nonresponse to
initial therapy. Lenalidomide has activity in a variety of hematologic malignancies, including …

Snow cover duration in a seasonally snow covered mountain range (San Juan Mountains,
USA) was found to be shortened by 18 to 35 days during ablation through surface shortwave …

The aim of this study was to inform the development of a questionnaire to assess a woman's
tendency to respond with sexual excitation/inhibition in different situations. Nine focus …