User profiles for "author:M Affolter"

Markus Affolter

Professor of Cell Biology, Biozentrum University of Basel
Verified email at unibas.ch
Cited by 20330

Homeodomain-DNA recognition

…, AF Schier, D Resendez-Perez, M Affolter… - Cell, 1994 - Elsevier
Homeodomain-DNA Recognition Review Page 1 Cell, Vol. 79, 211-223, July 29, 1994, Copyright
0 1994 by Cell Press Homeodomain-DNA Recognition Review Waiter J. Gehring; Yan Giu …

Homeodomain proteins

WJ Gehring, M Affolter, T Bürglin - Annual review of biochemistry, 1994 - annualreviews.org
Homeotic genes are master control genes that specify the body plan and regulate
development of higher organisms. They share a common sequence element of 180 bp, the …

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

M Affolter, K Basler - Nature Reviews Genetics, 2007 - nature.com
Morphogens have been linked to numerous developmental processes, including organ
patterning and the control of organ size. Here we review how different experimental …

[HTML][HTML] ESPRESSO at VLT-On-sky performance and first results

…, FM Zerbi, V Adibekyan, M Abreu, M Affolter… - Astronomy & …, 2021 - aanda.org
Context. ESPRESSO is the new high-resolution spectrograph of ESO's Very Large
Telescope (VLT). It was designed for ultra-high radial-velocity (RV) precision and extreme …

Protein–DNA contacts in the structure of a homeodomain–DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

G Otting, YQ Qian, M Billeter, M Müller, M Affolter… - The EMBO …, 1990 - embopress.org
The 1: 1 complex of the mutant Antp (C39––S) homeodomain with a 14 bp DNA fragment
corresponding to the BS2 binding site was studied by nuclear magnetic resonance (NMR) …

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

…, AN Economides, W Kwiatkowski, M Affolter… - Nature, 2002 - nature.com
The interplay between bone morphogenetic proteins (BMPs) and their antagonists governs
developmental and cellular processes as diverse as establishment of the embryonic dorsal …

Soluble forms of Toll-like receptor (TLR) 2 capable of modulating TLR2 signaling are present in human plasma and breast milk

…, M Grigorov, SD Lawn, M Affolter… - The Journal of …, 2003 - journals.aai.org
Dysregulation of the initial, innate immune response to bacterial infection may lead to septic
shock and death. Toll-like receptors (TLRs) play a crucial role in this innate immune …

Fluorescent fusion protein knockout mediated by anti-GFP nanobody

E Caussinus, O Kanca, M Affolter - Nature structural & molecular …, 2012 - nature.com
The use of genetic mutations to study protein functions in vivo is a central paradigm of
modern biology. Recent advances in reverse genetics such as RNA interference and …

OMICS-driven biomarker discovery in nutrition and health

M Kussmann, F Raymond, M Affolter - Journal of biotechnology, 2006 - Elsevier
While traditional nutrition research has dealt with providing nutrients to nourish populations,
it nowadays focuses on improving health of individuals through diet. Modern nutritional …

[HTML][HTML] Hox proteins meet more partners

RS Mann, M Affolter - Current opinion in genetics & development, 1998 - Elsevier
The Hox genes are clustered sets of homeobox-containing genes that play a central role in
animal development. Recent genetic and molecular data suggest that Hox proteins interact …