A New Respiratory Tract Pathogen: Chlamydia pneumoniae Strain TWAR

…, CC Kuo, CH Mordhorst, P Saikku… - Journal of Infectious …, 1990 - academic.oup.com
Chlamydia pneumoniae strain TWAR, the new third species of Chlamydia, is a common
cause of pneumonia and other acute respiratory tract infections. About 10% of hospitalized …

Natural products in the process of finding new drug candidates

P Vuorela, M Leinonen, P Saikku… - Current medicinal …, 2004 - ingentaconnect.com
Natural derived or originated compounds still play a major role as drugs, and as lead
structures for the development of synthetic molecules. About 50% of the drugs introduced to …

Evidence for infectious agents in cardiovascular disease and atherosclerosis

M Leinonen, P Saikku - The Lancet infectious diseases, 2002 - thelancet.com
During the past decade, several novel risk factors for atherosclerosis, including inflammation
and infections, have been reported. Seroepidemiological studies suggest an association …

Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction

P Saikku, K Mattila, MS Nieminen, JK Huttunen… - The Lancet, 1988 - Elsevier
Paired sera from 40 male patients with acute myocardial infarction (AMI), 30 male patients
with chronic coronary heart disease (CCHD), and 41 controls, matched for sex, age, time …

Viruses and bacteria in the etiology of the common cold

…, O Ruuskanen, M Leinonen, P Saikku… - Journal of clinical …, 1998 - Am Soc Microbiol
Two hundred young adults with common colds were studied during a 10-month period. Virus
culture, antigen detection, PCR, and serology with paired samples were used to identify the …

Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines

…, TG Harrison, D Rose, M Leinonen, P Saikku - Thorax, 2001 - thorax.bmj.com
BACKGROUND Since the last British study of the microbial aetiology of community acquired
pneumonia (CAP) about 20 years ago, new organisms have been identified (for example …

Chronic Chlamydia pneumoniae Infection as a Risk Factor for Coronary Heart Disease in the Helsinki Heart Study

P Saikku, M Leinonen, L Tenkanen… - Annals of internal …, 1992 - acpjournals.org
▪ Objective: To investigate in the prospective Helsinki Heart Study, whether chronic
Chlamydia pneumoniae infection, indicated by elevated antibody titers against the …

Serotypes of Chlamydia trachomatis and risk for development of cervical squamous cell carcinoma

T Anttila, P Saikku, P Koskela, A Bloigu, J Dillner… - Jama, 2001 - jamanetwork.com
ContextHuman papillomavirus (HPV) infection has been established as a cause of cervical
cancer. Epidemiologic studies suggest that Chlamydia trachomatis infection also confers …

Etiology of community-acquired pneumonia in 254 hospitalized children

…, M Roivainen, J Eskola, P Saikku… - The Pediatric …, 2000 - journals.lww.com
Background. Childhood community-acquired pneumonia is a common illness, but there
have been relatively few comprehensive studies of the viral and bacterial etiology in …

Infections, inflammation, and the risk of coronary heart disease

…, T Palosuo, P Toivanen, M Leinonen, P Saikku… - Circulation, 2000 - Am Heart Assoc
Background—The role of infections and inflammation in the pathophysiology of coronary
heart disease is emerging. We studied the independent and joint effects of these 2 …