Chronic hepatitis B virus (HBV) infection is overall recognised in 10% of HIV+ persons
worldwide, with large differences according to geographical region. Chronic hepatitis C virus …

Importance of the field: Tenofovir (TFV) is a nucleotide analogue widely used for the
treatment of HIV infection. Despite its proven efficacy and safety, cases of kidney tubular …

The approval of directly acting antivirals (DAA) for the treatment of chronic hepatitis C virus
(HCV) infection will represent a major breakthrough for the 180 million persons infected …

Background: Tenofovir (TDF) is the most widely prescribed antiretroviral drug. Kidney
abnormalities are the main concern using the drug. As glomerular function is infrequently …

Background. Tenofovir is one of the most widely used antiretroviral drugs. Tenofovir
undergoes renal clearance by a combination of glomerular filtration and active tubular …

Background. The risk of liver toxicity during antiretroviral drug use in human
immunodeficiency virus (HIV)-positive patients increases in the presence of chronic hepatitis …

Tenofovir (TFV) is a nucleotide analogue active against HIV and hepatitis B virus. Although
TFV rarely affects the glomerular function, abnormalities in the kidney tubular function …

Increasing numbers of HIV-serodiscordant heterosexual couples are concerned about the
chances for pregnancy. We reviewed all natural pregnancies attained by HIV-serodiscordant …

Patients infected with hepatitis C virus (HCV) have an impaired response against HCV
antigens while keeping immune competence for other antigens. We hypothesized that …

Background. Tenofovir (TFV) causes kidney tubular dysfunction (KTD) in some patients, but
the mechanism is poorly understood. Genetic variants in TFV transporters are implicated; we …