Purpose. To analyse the impact of computer-based patient record systems (CBPRS) on
medical practice, quality of care, and user and patient satisfaction. Data sources. Manual …

Anti-retroviral therapy partially restores the immune function of patients infected with human
immunodeficiency virus, thereby drastically reducing morbidity and mortality. However, the …

Objective: To assess the clinical and economic consequences of the use of protease
inhibitors in the treatment of HIV infection. Design: Multicentric, observational, retrospective …

Background Toxoplasmic encephalitis associated with immune reconstitution inflammatory
syndrome (TE-IRIS) is rarely described. Methods To identify TE-IRIS cases, the authors …

Background The clinical significance and cellular sources of residual human
immunodeficiency virus type 1 (HIV-1) production despite suppressive combination …

Inconsistent results have been reported for the semen quality in HIV‐infected men, due to
the biases inherent in some studies. The objective of the present study was to investigate the …

To develop new strategies aimed to reduce the delay in seeking HIV diagnosis, we
proposed to identify correlates of late diagnosis of HIV infection in France. Late testing was …

Abstract In the ANRS CO8 APROCO-COPILOTE cohort of patients treated with combination
antiretroviral therapy since 1997–1999, the incidence density of bone fractures was 3.3 for …

HIV-1 coreceptor usage plays a critical role for virus tropism and pathogenesis. A switch
from CCR5 to CXCR4-using viruses can occur in the natural course of infection and …

Background Long-term therapy with protease inhibitors (PI) is associated with
hypertriglyceridaemia, low high-density lipoprotein (HDL) levels and accumulation of …