[HTML][HTML] High-dose chemotherapy with autologous stem-cell support as adjuvant therapy in breast cancer: overview of 15 randomized trials
Purpose Adjuvant high-dose chemotherapy (HDC) with autologous hematopoietic stem-cell
transplantation (AHST) for high-risk primary breast cancer has not been shown to prolong …
transplantation (AHST) for high-risk primary breast cancer has not been shown to prolong …
Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial
…, TM Heinonen, S Kouz, C Berry, R Basser… - Jama, 2007 - jamanetwork.com
ContextHigh-density lipoprotein (HDL) cholesterol is an inverse predictor of coronary
atherosclerotic disease. Preliminary data have suggested that HDL infusions can induce …
atherosclerotic disease. Preliminary data have suggested that HDL infusions can induce …
[HTML][HTML] Response to a monovalent 2009 influenza A (H1N1) vaccine
ME Greenberg, MH Lai, GF Hartel… - … England Journal of …, 2009 - Mass Medical Soc
Background A novel 2009 influenza A (H1N1) virus is responsible for the first influenza
pandemic in 41 years. A safe and effective vaccine is needed. A randomized, observer …
pandemic in 41 years. A safe and effective vaccine is needed. A randomized, observer …
[HTML][HTML] Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors
SN Holden, SG Eckhardt, R Basser, R De Boer… - Annals of …, 2005 - Elsevier
Background:: ZD6474 selectively inhibits the tyrosine kinase activity of vascular endothelial
growth factor receptor and epidermal growth factor receptor. The safety, tolerability and …
growth factor receptor and epidermal growth factor receptor. The safety, tolerability and …
Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development …
RL Basser, E O'Flaherty, M Green… - Blood, The Journal …, 2002 - ashpublications.org
Clinical trials of thrombopoietin (TPO), the central regulator of megakaryocytopoiesis, have
revealed few side effects associated with its use. We here report a case of pancytopenia …
revealed few side effects associated with its use. We here report a case of pancytopenia …
Strategies for prevention of anthracycline cardiotoxicity
RL Basser, MD Green - Cancer treatment reviews, 1993 - Elsevier
Anthracycline antibiotics are among the most effective anticancer agents, with activity in a
wide range of solid and liquid tumors (1). Their use is associated with non-specific, clinically …
wide range of solid and liquid tumors (1). Their use is associated with non-specific, clinically …
Immunogenicity of a monovalent 2009 influenza A (H1N1) vaccine in infants and children: a randomized trial
…, R Booy, L Heron, G Hartel, M Lai, R Basser… - Jama, 2010 - jamanetwork.com
Context In the ongoing influenza pandemic, a safe and effective vaccine against 2009
influenza A (H1N1) is needed for infants and children. Objective To assess the …
influenza A (H1N1) is needed for infants and children. Objective To assess the …
Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX™ adjuvant in women with cervical intraepithelial neoplasia
IH Frazer, M Quinn, JL Nicklin, J Tan, LC Perrin, P Ng… - Vaccine, 2004 - Elsevier
PURPOSE:: Persistent infection of cervical epithelium with “high risk” human papillomavirus
(HPV) results in cervical intraepithelial neoplasia (CIN) from which squamous cancer of the …
(HPV) results in cervical intraepithelial neoplasia (CIN) from which squamous cancer of the …
A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute …
…, S Bamford, M Barnden, M DeWitte, R Basser… - Leukemia & …, 2015 - Taylor & Francis
Acute myeloid leukemia (AML) blasts express high levels of interlekin-3 (IL-3) receptor-α
(CD123). CSL360 is a recombinant, chimeric immunoglobulin G1 (IgG1), anti-CD123 …
(CD123). CSL360 is a recombinant, chimeric immunoglobulin G1 (IgG1), anti-CD123 …
Priming of CD4+ and CD8+ T cell responses using a HCV core ISCOMATRIX™ vaccine: A phase I study in healthy volunteers
…, B Gervase, S Coates, M Houghton, R Basser - Human …, 2009 - Taylor & Francis
The disease burden and public health impact of chronic HCV infection continues to be a
major problem globally. Current treatment for chronic HCV infection is not effective in all …
major problem globally. Current treatment for chronic HCV infection is not effective in all …