User profiles for "author:R K Lau"
Rebecca K LauUC San Diego Verified email at ucsd.edu Cited by 1298 |
An E1–E2 fusion protein primes antiviral immune signalling in bacteria
In all organisms, innate immune pathways sense infection and rapidly activate potent
immune responses while avoiding inappropriate activation (autoimmunity). In humans, the …
immune responses while avoiding inappropriate activation (autoimmunity). In humans, the …
[PDF][PDF] Structure and mechanism of a cyclic trinucleotide-activated bacterial endonuclease mediating bacteriophage immunity
Bacteria possess an array of defenses against foreign invaders, including a broadly
distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti …
distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti …
[PDF][PDF] HORMA domain proteins and a Trip13-like ATPase regulate bacterial cGAS-like enzymes to mediate bacteriophage immunity
Bacteria are continually challenged by foreign invaders, including bacteriophages, and have
evolved a variety of defenses against these invaders. Here, we describe the structural and …
evolved a variety of defenses against these invaders. Here, we describe the structural and …
Control of bacterial immune signaling by a WYL domain transcription factor
CL Blankenchip, JV Nguyen, RK Lau, Q Ye… - Nucleic acids …, 2022 - academic.oup.com
Bacteria use diverse immune systems to defend themselves from ubiquitous viruses termed
bacteriophages (phages). Many anti-phage systems function by abortive infection to kill a …
bacteriophages (phages). Many anti-phage systems function by abortive infection to kill a …
A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage
To protect themselves from the constant threat of bacteriophage (phage) infection, bacteria
have evolved diverse immune systems including restriction‐modification, CRISPR‐Cas, and …
have evolved diverse immune systems including restriction‐modification, CRISPR‐Cas, and …
Viral mumps: increasing occurrences in the vaccinated population
RK Lau, MD Turner - Oral Surgery, Oral Medicine, Oral Pathology and Oral …, 2019 - Elsevier
Before the introduction of the vaccine, mumps was the most common salivary gland disease
and was one of the most common infectious diseases in children globally. Following the …
and was one of the most common infectious diseases in children globally. Following the …
[HTML][HTML] Dynamic substrate preferences predict metabolic properties of a simple microbial consortium
Background Mixed cultures of different microbial species are increasingly being used to
carry out a specific biochemical function in lieu of engineering a single microbe to do the …
carry out a specific biochemical function in lieu of engineering a single microbe to do the …
[HTML][HTML] Web of microbes (WoM): a curated microbial exometabolomics database for linking chemistry and microbes
Background As microbiome research becomes increasingly prevalent in the fields of human
health, agriculture and biotechnology, there exists a need for a resource to better link …
health, agriculture and biotechnology, there exists a need for a resource to better link …
cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling
In all organisms, innate immune pathways sense viral infection and rapidly activate potent
immune responses while maintaining a high degree of specificity to prevent inappropriate …
immune responses while maintaining a high degree of specificity to prevent inappropriate …
Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates
A variety of genetic techniques have been devised to determine cell lineage relationships
during tissue development. Some of these systems monitor cell lineages spatially and/or …
during tissue development. Some of these systems monitor cell lineages spatially and/or …