Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in
epidemiological studies, increased triglyceride levels correlate with higher risk for coronary …

Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …

Advances in scientific computing have allowed the development of complex models that are
being routinely applied to problems in disease epidemiology, public health and decision …

Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …

Abstract The General Population Cohort (GPC) was set up in 1989 to examine trends in HIV
prevalence and incidence, and their determinants in rural south-western Uganda. Recently …

Approximate Bayesian Computation and Simulation-Based Inference for Complex Stochastic
Epidemic Models Page 1 Statistical Science 2018, Vol. 33, No. 1, 4–18 https://doi.org/10.1214/17-STS618 …

The linear mixed model (LMM) is now routinely used to estimate heritability. Unfortunately,
as we demonstrate, LMM estimates of heritability can be inflated when using a standard …

Abstract Background Non-communicable diseases (NCDs) are rapidly becoming leading
causes of morbidity and mortality in low-and middle-income countries, including those in sub …

Background The burden of dyslipidaemia is rising in many low income countries. However,
there are few data on the prevalence of, or risk factors for, dyslipidaemia in Africa. Methods …

Complex stochastic models are commonplace in epidemiology, but their utility depends on
their calibration to empirical data. History matching is a (pre) calibration method that has …