User profiles for "author:Rita Castro"

Rita Castro

- Verified email at psu.edu - Cited by 3463

Rita Castro

- Verified email at staff.uma.pt - Cited by 630

Rita Castro

- Verified email at deb.uminho.pt - Cited by 363

Epigenetic modifications: basic mechanisms and role in cardiovascular disease

DE Handy, R Castro, J Loscalzo - Circulation, 2011 - Am Heart Assoc
The term epigenetics was first used to refer to the complex interactions between the genome
and the environment that are involved in development and differentiation in higher …

[HTML][HTML] The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art

R Esse, M Barroso, I Tavares de Almeida… - International journal of …, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …

Increased Homocysteine and S-Adenosylhomocysteine Concentrations and DNA Hypomethylation in Vascular Disease

R Castro, I Rivera, EA Struys, EEW Jansen… - Clinical …, 2003 - academic.oup.com
Background: The pathogenic mechanism of homocysteine's effect on cardiovascular risk is
poorly understood. Recent studies show that DNA hypomethylation induced by increases in …

[HTML][HTML] The link between hyperhomocysteinemia and hypomethylation: Implications for cardiovascular disease

M Barroso, DE Handy, R Castro - … of Inborn Errors of Metabolism and …, 2019 - SciELO Brasil
Increased levels of homocysteine have been established as a risk factor for cardiovascular
disease (CVD) by mechanisms still incompletely defined. S-Adenosylhomocysteine (SAH) is …

Evaluation of an Enzyme Immunoassay Technique for Detection of Antibodies against Treponema pallidum

R Castro, ES Prieto, I Santo, J Azevedo… - Journal of Clinical …, 2003 - Am Soc Microbiol
In the present study, the performance of an enzyme-linked immunosorbent assay (ELISA)
technique (Eti-syphilis-G and Eti-syphilis-M; DiaSorin) for detection of Treponema pallidum …

Electrospun laponite-doped poly (lactic-co-glycolic acid) nanofibers for osteogenic differentiation of human mesenchymal stem cells

S Wang, R Castro, X An, C Song, Y Luo… - Journal of Materials …, 2012 - pubs.rsc.org
We report the fabrication of uniform electrospun poly (lactic-co-glycolic acid)(PLGA)
nanofibers incorporated with laponite (LAP) nanodisks, a synthetic clay material for …

Thermophilic co-digestion of organic fraction of municipal solid wastes with FOG wastes from a sewage treatment plant: reactor performance and microbial community …

L Martín-González, R Castro, MA Pereira… - Bioresource …, 2011 - Elsevier
Working at thermophilic conditions instead of mesophilic, and also the addition of a co-
substrate, are both the ways to intend to improve the anaerobic digestion of the source …

[HTML][HTML] Predictors of enhancing human physical attractiveness: Data from 93 countries

M Kowal, P Sorokowski, K Pisanski… - Evolution and Human …, 2022 - Elsevier
People across the world and throughout history have gone to great lengths to enhance their
physical appearance. Evolutionary psychologists and ethologists have largely attempted to …

Nontreponemal tests in the diagnosis of neurosyphilis: an evaluation of the Venereal Disease Research Laboratory (VDRL) and the Rapid Plasma Reagin (RPR) tests

R Castro, ES Prieto… - Journal of clinical …, 2008 - Wiley Online Library
Abstract The Venereal Disease Research Laboratory (VDRL) test has long been considered
the best serological test for the diagnosis of neurosyphilis. The goal of this study was to find …

PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia

SD Santos, M Xavier, DM Leite, DA Moreira… - Journal of controlled …, 2018 - Elsevier
Drug delivery to the central nervous system is restricted by the blood-brain barrier (BBB).
However, with the onset of stroke, the BBB becomes leaky, providing a window of …