[HTML][HTML] Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

S Cele, L Jackson, DS Khoury, K Khan, T Moyo-Gwete… - Nature, 2022 - nature.com
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B. 1.1. 529),
first identified in Botswana and South Africa, may compromise vaccine effectiveness and …

[HTML][HTML] Long COVID: a review and proposed visualization of the complexity of long COVID

R Perumal, L Shunmugam, K Naidoo… - Frontiers in …, 2023 - frontiersin.org
Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2)
infection, or Long COVID, is a prevailing second pandemic with nearly 100 million affected …

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

Q Abdool Karim, SS Abdool Karim, JA Frohlich… - science, 2010 - science.org
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed
the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide …

[HTML][HTML] Durability of vaccine-induced and natural immunity against COVID-19: a narrative review

N Pooley, SS Abdool Karim, B Combadière… - Infectious Diseases and …, 2023 - Springer
Vaccines developed against SARS-CoV-2 have proven to be highly effective in preventing
symptomatic infection. Similarly, prior infection with SARS-CoV-2 has been shown to provide …

[HTML][HTML] New SARS-CoV-2 variants—clinical, public health, and vaccine implications

SS Abdool Karim, T de Oliveira - New England Journal of …, 2021 - Mass Medical Soc
New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications | NEJM Skip to
main content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare …

[HTML][HTML] Timing of initiation of antiretroviral drugs during tuberculosis therapy

SS Abdool Karim, K Naidoo, A Grobler… - … England Journal of …, 2010 - Mass Medical Soc
Background The rates of death are high among patients with coinfection with tuberculosis
and the human immunodeficiency virus (HIV). The optimal timing for the initiation of …

[HTML][HTML] Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

NA Doria-Rose, CA Schramm, J Gorman, PL Moore… - Nature, 2014 - nature.com
Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the
HIV-1 envelope, but the mechanism of their elicitation has been unclear. Here we define the …

[HTML][HTML] Omicron BA. 4/BA. 5 escape neutralizing immunity elicited by BA. 1 infection

K Khan, F Karim, Y Ganga, M Bernstein, Z Jule… - Nature …, 2022 - nature.com
Abstract SARS-CoV-2 Omicron (B. 1.1. 529) BA. 4 and BA. 5 sub-lineages, first detected in
South Africa, have changes relative to Omicron BA. 1 including substitutions in the spike …

Clinical trials of broadly neutralizing monoclonal antibodies for human immunodeficiency virus prevention: a review

S Mahomed, N Garrett, C Baxter… - The Journal of …, 2021 - academic.oup.com
Passive immunization with broadly neutralizing antibodies (bnAbs) is a promising approach
to reduce the 1.7 million annual human immunodeficiency virus (HIV) infections globally …

[HTML][HTML] Integration of antiretroviral therapy with tuberculosis treatment

SS Abdool Karim, K Naidoo, A Grobler… - … England Journal of …, 2011 - Mass Medical Soc
Background We previously reported that integrating antiretroviral therapy (ART) with
tuberculosis treatment reduces mortality. However, the timing for the initiation of ART during …